Infectious Diseases Watch with Dr. Ed

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Infectious Diseases Watch with Dr. Ed

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Edward J. Septimus, M.D., F.I.D.S.A, F.A.C.P, F.S.H.E.A.

Dr. Ed Septimus received his medical degree from Baylor College of Medicine in Houston in 1972. Dr. Septimus went on to complete his postgraduate training in internal medicine and infectious diseases at Baylor College of Medicine in Houston. Dr. Ed Septimus is board certified in both internal medicine and infectious diseases. He was VP Research and…

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Clinicians of the Future-VII Editorial; Intravenous to Oral Antibiotic Switch Therapy Among Patients Hospitalized with Community-Acquired Pneumonia; Effects of Patient Beliefs Regarding the Need for Antibiotics and Prescribing Outcomes on Patient Satisfaction in Urgent-Care Settings, Sulbactam-durlobactam; Seres Therapeutics SEP-109 (Vowst); VE303, a Defined Bacterial Consortium, for Prevention of Recurrent Clostridioides difficile Infection A Randomized Clinical Trial; Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridioides difficile (Clostridium difficile); Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections; STDs are on the Rise - New CDC Report; Epidemiology and Outcomes of Hospital-Acquired Bloodstream Infections in Intensive Care Unit Patients: the EUROBACT-2 International Cohort Study; Epidemiology, Resistance Profiles, and Outcomes of Bloodstream Infections in Community-Onset Sepsis in the United States; Incidence, Complications, and Costs of Peripheral Venous Catheter-Related Bacteraemia: A Retrospective, Single-Centre Study; Utility of Differential Time to Positivity in Diagnosing Central Line Associated Bloodstream Infections: A Systematic Review and Meta-Analysis; Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults; Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants; Reduced Respiratory Syncytial Virus Load, Symptoms, and Infections: A Human Challenge Trial of MVA-BN-RSV Vaccine; Increase in Pediatric Invasive Group A Streptococcus Infections(iGAS) — Colorado and Minnesota, October–December 2022; Worldwide Prevalence of Antibiotic-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis A Systematic Review and Meta-Analysis; European Centre for Disease Prevention and Control (ECDC) Released on COVID Vaccination; FDA and CDC Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines; SARS-CoV-2 Neutralising Antibodies After Bivalent Versus Monovalent Booster; Durability of Bivalent Boosters Against Omicron Subvariants; Association of SARS-CoV-2 Vaccination or Infection with Bell Palsy A Systematic Review and Meta-Analysis; COVID-19 by the Numbers; Arcturus (formally, Omicron subvariant XBB.1.16) Now a VOI and XBB.1.9.1; Virological Characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant; IDSA Guideline on the Treatment and Management of COVID-19 Update-Convalescent Plasma; The US FDA Gives an EUA for a New Monoclonal Antibody Treatment (vilobelimab); Optimal Duration of Systemic Corticosteroids in Coronavirus Disease 2019 Treatment: A Systematic Review and Meta-Analysis; Higher Dose Corticosteroids in Patients Admitted to Hospital With COVID-19 Who are Hypoxic but Not Requiring Ventilatory Support (RECOVERY): A Randomised, Controlled, Open-Label, Platform Trial; SARS-CoV-2 Variants and Multisystem Inflammatory Syndrome in Children; Risk of Death in Patients Hospitalized for COVID-19 vs Seasonal Influenza in Fall-Winter 2022-2023; SARS-CoV-2 During Omicron Variant Predominance Among Infants Born to People With SARS-CoV-2; Original Investigation | Pediatrics Assessment of Neurodevelopment in Infants With and Without Exposure to Asymptomatic or Mild Maternal SARS-CoV-2 Infection During Pregnancy; Maternal SARS-CoV-2, Placental Changes and Brain Injury in 2 Neonates; Sickness Presenteeism in Healthcare Workers During the Coronavirus Disease 2019 (COVID-19) Pandemic: An Observational Cohort Study; Association Between Stopping Universal SARS-CoV-2 Admission Testing and Hospital-Onset SARS-CoV-2 in England and Scotland; Universal Masking in Health Care Settings: A Pandemic Strategy Whose Time Has Come and Gone, For Now

May 2023

Nipah Outbreak in Bangladesh; Marburg Virus Equatorial Guinea; Effect of Antibiotic Prescription Audit and Feedback on Antibiotic Prescribing in Primary Care; COVID-19 and Outpatient Antibiotic Prescriptions in the United States, Antimicrobial for 7 or 14 Days for Febrile Urinary Tract Infection in Men, A Multicenter Noninferiority Double Blind Placebo-Controlled, Randomized Clinical Trial; How Climate Change is Spreading Malaria in Africa; Rapid Range Shifts in African Anopheles Mosquitoes Over the Last Century; Real-World Use of Bezlotoxumab and Fecal Microbiota Transplantation for the Treatment of Clostridioides difficile Infection; Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection: A Phase 3, Open-Label, Single-Arm Trial; Screening for Clostridioides difficile Colonization at Admission to the Hospital; The Impact of Timing of Infectious Disease Consultation for Staphylococcus Aureus Bacteremia; Health Disparities in Hemodialysis-Associated Staphylococcus Aureus Bloodstream Infections; People-Centred Framework for Addressing Antimicrobial Resistance in the Human Health Sector; Association of Proton Pump Inhibitor Use with Risk of Acquiring Drug-Resistant Enterobacterales; Increase in Extensively Drug-Resistant Shigellosis; Mpox in People with Advanced HIV Infection; CDC Panel Recommends Jynneos Vaccine for All Adults at Risk; Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations; Household Transmission of Influenza A Viruses in 2021-2022; Respiratory Syncytial Virus Disease Burden in Community-Dwelling and Long-Term Care Facility Older Adults in Europe and the United States; FDA Advisors Recommend First-Ever RSV Vaccines for Adults; Physical Interventions to Interrupt or Reduce the Spread of Respiratory Viruses; First At-Home Combination Test for Flu and Covid-19; Covid-19 Impact: Three Year Anniversary; Lab Leak Most Likely Origin of Covid-19 Pandemic; Wastewater-Based Monitoring of SARS-Cov-2 at UK Airports and Its Potential Role in International Public Health Surveillance; Aircraft Wastewater Surveillance for Early Detection of SARS-Cov-2 Variants — JFK International Airport; Effect of Predeparture Testing on Postarrival SARS-Cov-2–Positive Test Results Among International Travelers — CDC Traveler-Based Genomic Surveillance Program; Viral Burden Rebound in Hospitalised Patients With COVID-19 Receiving Oral Antivirals in Hong Kong; Association of COVID-19 Vaccination with Risk for Incident Diabetes After COVID-19 Infection; Past SARS-Cov-2 Infection Protection Against Re-Infection; Rethinking Next-Generation Vaccines for Coronaviruses, Influenza Viruses, and Other Respiratory Viruses; Assessment of COVID-19 as the Underlying Cause of Death Among Children and Young People Aged 0 To 19 Years in the US; Hospital Outcomes of Community-Acquired SARS-Cov-2 Omicron Variant Infection Compared with Influenza Infection in Switzerland; Symptom and Viral Rebound in Untreated SARS-Cov-2 Infection; Impact of Vaccination on Major Adverse Cardiovascular Events in Patients With COVID-19 Infection; Effectiveness of Bivalent Mrna Booster Vaccination Against SARS-Cov-2 Omicron Infection; Bivalent Booster Effectiveness Against Severe COVID-19 2 Outcomes; Effects of Remdesivir in Patients Hospitalised With COVID-19

March 2023

Physician 2022 Burnout Rates, Piperacillin Nephrotoxicity is Driven by Elevated Serum Trough Concentrations, Going Back in Time: Increasing Penicillin Susceptibility Among Methicillin-Susceptible Staphylococcus Aureus Osteoarticular Infections in Children, Probiotic for Pathogen-Specific Staphylococcus Aureus Decolonisation in Thailand, FDA Panel Recommends Rezafungin as New Candida Treatment, 2 Days vs. 5 Days of Postoperative Antibiotics for Complex Appendicitis, Multicentre, Noninferiority Randomised Trial, Norovirus National Trends, Outbreak of Extensively Drug-Resistant Pseudomonas Aeruginosa Associated With Artificial Tears, Comparing Complication Rates of Midline Catheter vs. Peripherally Inserted Central Catheter (PICC), High Dose Cefepime vs. Carbapenems for Bacteremia Caused by Enterobacterales With Moderate to High Risk of Clinically Significant Ampc Β-Lactamase Production, Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth, Worst Avian Flu in U.S. History Is Hitting Poultry, Wild Birds, Even Bears, Bird Flu Has Begun to Spread in Mammals, Codetections of Other Respiratory Viruses Among Children Hospitalized With COVID-19, A Pragmatic Randomized Feasibility Trial of Influenza Vaccines, HHS Weekly Report (Influenza/RSV), The Influence of Rapid Influenza Diagnostic Testing on Clinician Decision-Making for Patients With Acute Respiratory Infection in Urgent Care, Sensitivity of RIDTs for Influenza, US Plans to End Public Health Emergency for Covid-19 in May, Covid-19 by the Numbers, FDA Removes Positive COVID-19 Test Requirement for Antiviral Treatments, Available Outpatient Covid-19 Treatments, Information for Persons Who are Immunocompromised Regarding Prevention and Treatment of SARS-Cov-2 Infection in the Context of Currently Circulating Omicron Sublineages, FDA Withdraws EUA for Tixagevimab/Cilgavimab, IDSA Updated Guideline for COVID-19, Early Treatment With Pegylated Interferon Lambda for Covid-19, Children and COVID: Weekly Cases, Assessment of Efficacy and Safety of Mrna COVID-19 Vaccines in Children Aged 5 to 11 Years, Adverse Events Following the BNT162b2 Mrna COVID-19 Vaccine (Pfizer-Biontech) in Aotearoa New Zealand, Novavax NVX COV2373 Triggers Neutralization of Omicron Sub Lineages, Early Estimates of Bivalent Mrna Booster Dose Vaccine Effectiveness in Preventing Symptomatic SARS-Cov-2 Infection Attributable to Omicron BA.5– And XBB/XBB.1.5–Related Sublineages Among Immunocompetent Adults — Increasing Community Access to Testing Program, COVID-19 Incidence and Mortality Among Unvaccinated And Vaccinated Persons Aged ≥12 Years by Receipt of Bivalent Booster Doses and Time Since Vaccination, Protective Effectiveness of Previous SARS-Cov-2 Infection and Hybrid Immunity Against the Omicron Variant and Severe Disease

February 2023

Efficacy and Safety of Azithromycin vs Placebo to Treat Lower Respiratory Tract Infections Associated with Low Procalcitonin; Association of Appropriate Empirical Antimicrobial Therapy with In-Hospital Mortality in Patients with Bloodstream Infections; Antimicrobial Resistance and Mortality Following E. Coli Bacteremia; Antibiotic Use as a Risk Factor for Inflammatory Bowel Disease; Machine Learning to Stratify Methicillin-Resistant Staphylococcus Aureus Risk Among Hospitalized Patients with Community-Acquired Pneumonia; Defining Optimal Duration of Therapy for Hospitalized Patients with Complicated Urinary Tract Infections and Associated Bacteremia; Risk Factors Associated with Antimicrobial Resistance and Adverse Short-Term Health Outcomes Among Adult and Adolescent Female Outpatients with Uncomplicated UTI; Association of Pneumococcal Conjugate Vaccine Use with Hospitalized Pneumonia in Medicare Beneficiaries 65 Years or Older; Proposed HHS National Action Plan; Antibiotic Concentrations and Antibiotic Resistance in Aquatic Environments of the WHO Western Pacific and South-East Asia Regions; Uganda’s Ebola Outbreak; FDA OKs Tdap Shot in Pregnancy to Protect Newborns from Pertussis; Vaccination Coverage with Selected Vaccines and Exemption Rates Among Children in Kindergarten; Moderna Reports RSV Vaccine Cuts Risk of Respiratory Diseases in Older Adults; The Young Were Not Spared: What Death Certificates Reveal About Non-Covid Excess Deaths; Commentary: Covid-19 Year 4; Are Americans Dying from Covid-19 or with Covid-19?; WHO’s Updated Covid Guidelines; US Renews Health Emergency; NIH Updates Regarding Use of Bebtelovimab; CDC & FDA Identify Preliminary Covid Vaccine Safety Signal for Persons Aged 65 Years and Older; Combined IDSA/SHEA Statement: U.S. Must Consider Broader Measures to Mitigate COVID-19 Transmission; Covid by Numbers; Infectiousness of SARS-Cov-2 Breakthrough Infections and Reinfections During Omicron Wave; Protection Against Symptomatic Infection with Delta and Omicron BA.1 and BA.2 SARS-Cov-2 Variants After Previous Infection and Vaccination in Adolescents; Enhanced Transmissibility of XBB.1.5 is Contributed by Both Strong ACE2 Binding and Antibody Evasion; Neutralisation Sensitivity of the SARS-Cov-2 XBB.1 Lineage; COVID-19 Convalescent Plasma for Treatment of Immunocompromised Patients; Effectiveness of Bivalent mRNA Vaccine in Preventing Severe Covid Outcomes; Impaired CD4+ T Cell Response in Older Adults is Associated with Reduced Immunogenicity and Reactogenicity of mRNA Vaccination; Outcomes Among Mechanically Ventilated Patients with Severe Pneumonia and Acute Hypoxemic Respiratory Failure from SARS-Cov-2 and Other Etiologies; Long Covid Outcomes at One Year After Mild SARS-Cov-2 Infection; Long COVID: Major Findings, Mechanisms and Recommendations

January 23, 2023

General Infectious Diseases: Shortage of Infectious Disease Physicians, Impact of Rapid Molecular Test for Klebsiella pneumoniae Carbapenemase and Ceftazidime-Avibactam Use on Outcomes After Bacteremia Caused by Carbapenem–Resistant Enterobacterales, Case-Control Study Evaluating Unnecessary Use of Intravenous Broad-Spectrum Antibiotics in Presumed Sepsis and Septic-Shock Patients, Association of Follow-Up Blood Cultures with Mortality in Patients with Gram-Negative Bloodstream Infections a Systematic Review and Meta-Analysis, Increase in Pediatric Invasive Group A Streptococcal Infections, Association of Adverse Events with Antibiotic Treatment for Urinary Tract Infection; Mpox: Surveillance, Case Investigation and Contact Tracing for Monkeypox: Interim Guidance, Mpox by Numbers, Clinical Features and Management of Individuals Admitted Hospital with Monkeypox and Associated Complications Across the UK; Respiratory Viruses (Not SARS-Cov-2): Prevalence of SARS-Cov-2 and Influenza Coinfection and Clinical Characteristics Among Children and Adolescent Aged, Influenza Vaccine Effectiveness Against Influenza A(H3N2)- Related Illness in United States During 2021–2022 Influenza Season, Respiratory Viruses by Numbers; COVID-19: Covid-19 Risk Continuum, US Offers Free At-Home Tests Again, US to Require Negative Tests for Travelers Coming from China, IDSA Update on Antigen Testing, Covid-19 by Numbers, Association of Time to Surgery After Infection with Risk of Postoperative Cardiovascular Morbidity, Asymptomatic Screening for Severe Acute Respiratory Coronavirus Virus 2 (SARS-Cov-2) as an Infection Prevention Measure in Healthcare Facilities: Challenges and Considerations, SARS-Cov-2 Infection History and Antibody Response to Three Mrna Vaccine, Molnupiravir Plus Usual Care Versus Usual Care Alone as Early Treatment for Adults with COVID at Increased Risk of Adverse Outcomes (PANORAMIC): An Open-Label, Platform Adaptive Randomised Controlled Trial, VV116 Versus Nirmatrelvir–Ritonavir for Oral Treatment, High Titers of Infectious SARS-Cov-2 in COVID Corpses, Postmortem Stability of SARS-Cov-2 in Nasopharyngeal Mucosa, Infectivity of Deceased COVID Patients, SARS-Cov-2 Infection and Persistence in Human Body and Brain at Autopsy, Council of State and Territorial Epidemiologists/CDC Surveillance Case Definition for Multisystem Inflammatory Syndrome in Children Associated with SARS-Cov-2 Infection, Alarming Antibody Evasion Properties of Rising SARS-Cov-2 BQ and XBB Subvariants, Early Estimates of Bivalent Mrna Vaccine Effectiveness in Preventing COVID – Associated Emergency Department or Urgent Care Encounters and Hospitalizations Among Immunocompetent Adults, Early Estimates of Bivalent Mrna Vaccine Effectiveness in Preventing COVID – Associated Hospitalization Among Immunocompetent Adults Aged ≥65 Years, Predictors of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Following High-Risk Exposure, Impact of SARS-Cov-2 Variants on Inpatient Clinical Outcome, Outcomes and Adverse Effects of Baricitinib Versus Tocilizumab in the Management of Severe COVID

January 1, 2023

General Infectious Diseases: Anti-Anaerobic Antibiotics Increase Risk of Adverse Clinical Outcomes In Critically Ill Patients, Effect of Selective Decontamination of Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation, Association Between Selective Decontamination of Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation, FDA OKs First Fecal Transplant Therapy for Recurrent C Difficile, Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double Blind, Placebo Controlled Trial, Progress Toward Regional Measles Elimination, Respiratory Viruses: RSV by Numbers, Influenza by Numbers, VE of Influenza Vaccination of Pregnant for Prevention of Maternal and Early Infant Hospitalizations in South Africa, A Multivalent Nucleoside-Modified Mrna Vaccine Against All Known Influenza Virus Subtypes, Mpox: Mpox by Numbers, Single and 2-Dose Vaccinations with Modified Vaccinia Ankara-Bavarian Nordic® Induce Durable B Cell Memory Responses, Reduced Risk for Mpox After Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk of Unvaccinated, COVID-19: FDA Authorizes Updated Covid Vaccines for Children as Young As 6 Months, Here We Go Again and Covid by Numbers, Bebtelovimab Update, Association of COVID with Diabetes: A Systematic Review and Meta Analysis, Free Fatty Acid–Binding Pocket is a Conserved Hallmark in Pathogenic Β-Coronavirus Spike Proteins from SARS-Cov to Omicron, Shifting Mortality Dynamics in US During Covid Pandemic as Measured by Years of Life Lost, Medical Masks vs N95 Respirators for Preventing Covid Among Health Care Workers, Association of Initial SARS-Cov-2 Test Positivity with Patient-Reported Well-Being 3 Months After Symptomatic Illness, VE of Mrna-1273, BNT162b2, and BBIBP-Corv Vaccines Against Infection and Mortality in Children in Argentina, SARS-Cov-2 Viral Load and Shedding Kinetics, Low Neutralization of SARS-Cov-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by Parental Mrna Vaccine or a BA.5-Bivalent Booster, Efficacy of Antiviral Agents Against Omicron Subvariants BQ.1.1 and XBB, Twice-Daily Oral Zinc in Treatment of Patients with Coronavirus Disease 2019: A Randomized Double-Blind Controlled Trial

December 12, 2022

General Infectious Diseases: Early Mobilization Mechanical Ventilation in ICU, AR in EU, Increase in Bsis with CRAB 2020 and 2021 in EU, Infection Prevention Staffing Levels and Hais, Global Mortality Associated with 33 Bacterial Pathogens in 2019, 5-Ethyl-2-Deoxyuridine K Pneumoniae Intracellular Killing, Clinical Impact of Ceftriaxone Resistance in E Coli BSI, Evaluation of Opt-Out Protocol for De-Escalation in Sepsis, Discontinuing MRSA And VRE Contact Precautions; Respiratory Viruses: Association Between Influenza Vaccination and Risk of Stroke, Influenza Vaccine to Reduce Adverse Vascular Events in Patients with Heart Failure, Influenza by the Numbers, Other Respiratory Viruses by the Numbers; Monkeypox: WHO Renames Monkeypox, Monkeypox by Numbers, Mutations in Virus Replication, Tecovirimat Resistance, Human Monkeypox in Women and Non-Binary Individuals, Effectiveness of One Dose of MVA-BN Smallpox Vaccine Against Monkeypox; COVID-19: Moderna Bivalent Booster, Pfizer Bivariant Against BQ.1.1, Covid by Numbers, Covid No Longer Mainly a Pandemic of the Unvaccinated, Changes in Population Immunity Against Infection and Severe Disease from Omicron Variants, Effectiveness of Bivalent Mrna Vaccines in Preventing Symptomatic Infection, Paxlovid Associated with Decreased Hospitalization Rate Among Adults, Prevalence of Contraindications to Nirmatrelvir-Ritonavir, Diagnostic Accuracy of Rapid Antigen Self-Tests in Asymptomatic Individuals, Covid and Excess All-Cause Mortality in the US and 20 Comparison Countries, Omicron Sublineage BQ.1.1 Resistance to Monoclonal Antibodies, Saliva Antibody-Fingerprint of Reactivated Viruses After Mild/Asymptomatic Covid, Vaccine Effectiveness Against Reinfection

November 28, 2022

Safety and Efficacy of a Monoclonal Antibody Against Malaria in Mali, Routine Sterile Glove and Instrument Change at the Time of Abdominal Wound Closure to Prevent Surgical Site Infection, Comparative Safety and Health Care Expenditures Following Inappropriate Versus Appropriate OP Antibiotic URI, Viral Shedding 1 Year Following First-Episode Genital HSV-1 Infection, 2021 HAI Progress Report; Monkeypox: HHA Renews Public Health Emergency, Monkeypox by Numbers, Transmission Dynamics of MPXV in UK, Epidemiol and Clinical Features Children and Adolescents with MPXV, Global MPXV Hospitalization Rates; Influenza and RSV, Influenza Rates in US, RSV Rates in US; COVID-19: The Rise of BQ, Covid by Numbers, HHS Extend Health Emergency, Pfizer Bivalent Vaccine Study, EUA Anakinra, AAP Report, Hospitalizations Among US Infants, Variants to Watch, Safety Monitoring of Bivalent Vaccine Booster Persons ≥12 Years, Gut Microbiome Dysbiosis in Antibiotic Treated Patients with Bsis, Health Impairment in Children and Adolescents After Hospitalization with MIS-C, Comparative Risk Myocarditis/Pericarditis After Second Dose of Pfizer and Moderna, Protection Against Omicron from Vaccination and Previous Infection in Prison System, Fostamatinib for Treatment of Hospitalized Adults, VL Dynamics Delta and Omicron Variants Following Vaccination and Previous Infection, Nirmatrelvir and Risk of Post-Acute Sequelae, Translation Feasibility and Efficacy of Nasal Photodynamic Disinfection of SARS-Cov-2, Lifting Universal Masking in Schools, Acute and Postacute Sequelae Associated with Reinfection

November 14, 2022

Diagnostic Accuracy of Bacterial and Viral Biomarker Point-of-Care Test in Outpatient Setting, Effectiveness of Ultraviolet-C Disinfection on Hospital-Onset Gram-Negative Rod Bloodstream Infection, Clinical Impact of Ceftriaxone Resistance in Escherichia Coli Bloodstream Infections, Changes in Burnout and Satisfaction with Work-Life Integration in Physicians During the First 2 Years of the COVID-19 Pandemic, Ebola: Uganda as Outbreak Grows to 100 Confirmed Cases; Fungal Report: WHO Fungal Priority Pathogens List to Guide Research, Development, and Public Health Action; Evolution of the Human Pathogenic Lifestyle in Fungi, Increased Deaths from Fungal Infections During the COVID-19 Pandemic, Pan-Cancer Mycobiome Analysis Reveals Fungal Involvement in Gastrointestinal and Lung Tumors; Respiratory Viruses: Tripledemic?, Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity, Influenza and COVID-19 Vaccination Coverage Among Health Care Personnel; Monkeypox: Ocular Monkeypox, Infection Resulting from an Occupational Needlestick, Severe Monkeypox in Hospitalized Patients, Monkeypox by Numbers; COVID-19: FDA Authorizes Novavax as Booster for Adults, ACIP Support Adding Vaccines to Regular Immunizations, Variants BQ.1 and BQ.1.1, NIH COVID-19 Treatment Guidelines Panel’s Statement on Omicron Subvariants and Anti-SARS-CoV-2 Monoclonal Antibodies, Covid by Numbers, GAO Report: Maternal Health, Multicenter Comparison of Prevalence and Predictors of Antimicrobial Resistance in Hospitalized Patients Before and During Pandemic, Estimated Protection of Prior Infection Against Reinfection with the Omicron Variant Among Messenger RNA, Adverse Childhood Experiences During and Associations with Poor Mental Health and Suicidal Behaviors Among High School Students, Clinical Effectiveness and Safety of Remdesivir in Hemodialysis Patients with Covid, Association of mRNA Vaccination with Clinical and Virologic Features of Covid Among US Essential and Frontline Workers, Prevalence of Positive Rapid Antigen Tests After 7-Day Isolation Following Infection in College Athletes During Omicron Variant Predominance, Neutralization Escape by Omicron Subvariant BA.4.6, Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients with Mild to Moderate Covid, Antibody Responses to Omicron BA.4/BA.5 Bivalent mRNA Vaccine Booster, Immunogenicity of the BA.5 Bivalent mRNA Vaccine Boosters, Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients with Covid

October 31, 2022

General Infectious Diseases: FDA Pertussis Vaccine Approval, Outbreak Ebola Virus Central Uganda, Transmission of Carbapenem KP in US Hospitals, Correlation of Pyuria and Bacteriuria, Administration of a β-lactam Prior to Vancomycin; Influenza: 2022 National Survey: Attitudes about Influenza and Pneumococcal Disease and Impacts of Covid, US Flu Activity; Monkeypox: FDA EUA for New Monkeypox Test, Risk of Monkeypox Transmission to HCP, Epidemiological and Clinical Characteristics of Patients with Monkeypox, COVID: APIC Response to Lifting Universal Masking, Variant Updates, Covid by Numbers, XBB Variant, Evusheld Against BA.4.6, Commonwealth Analysis on Boosters, Preliminary on Pfizer Bivalent Vaccine, Novavax Booster, Pediatric Antibody Prevalence, FDA Approval Bivalent Boosters Ages 5-11; Clinical, Virologic, and Immunologic Evaluation Rebound Following Nirmatrelvir/Ritonavir, Diagnostic Accuracy of Rapid Antigen Tests with Unsupervised Self-Sampling, Clinical and Genetic Risk Factors VTE in Ambulatory Patients, Peripartum Outcomes Associated with Vaccination During Pregnancy, Impact of SARS-CoV-2 Vaccination and Boosters on Symptom Severity, Association Between Vaccination Status and Mortality Among Intubated Patients, Effectiveness and Durability of Pfizer Vaccine Against Hospitalization and ED Admissions, Severe Outcomes after Full Vaccination and Initial Booster, New Symptoms and Prevalence of Postacute Covid-19 Among Nonhospitalized Survivors, Molnupiravir Versus Usual Care in Early Treatment

October 17, 2022

Mupirocin Susceptibility of Staphylococci, Efficacy of Different Preoperative Skin Antiseptics on Incidence of Surgical Site Infections, Norovirus Outbreaks Reported Through NoroSTAT, Increase in Acute Respiratory Illnesses Among Children and Adolescents Associated with Rhinoviruses and Enteroviruses, Including Enterovirus D68, FDA Votes in Favor of Fecal Transplant Therapy RBX2660 for Recurrent C. difficile Infection, Influenza Vaccines 2022-3, “Twindemic” Risk, Repeated Influenza Vaccination Effectiveness, Monkeypox: Severe Manifestations of MPXV Among People Who are Immunocompromised, Neurologic Complications of Smallpox and Monkeypox A, Effectiveness of a Single-Dose Modified Vaccinia Ankara in Human Monkeypox, Monkeypox by the Numbers, COVID-19: BA.5.2.1.7 (BF.7 for short), CDC Revises Masking Guidance for Healthcare Facilities, CDC Revised Its "Up to Date" Vaccination, COVID by the Numbers, Emotional Exhaustion Among US HCWs Before and During Pandemic, Long-Term Neurologic Outcomes of COVID-19, Association of SARS-CoV-2 Infection With New-Onset Type 1 DM Among Pediatric Patients, Odds of Hospitalization After 3 vs 2 Doses of mRNA Vaccine by Time Since Booster, Protection Against BA.2 Reinfection Conferred by Primary Omicron BA.1 or Pre-Omicron SARS-CoV-2 Infection Among HCWs With and Without mRNA Vaccination, Longitudinal Eval of AB Persistence in Mother-Infant Dyads Following SARS-CoV-2 Infection in Pregnancy, MRSA Bacteremia During Pandemic

October 2, 2022

Risk Factors and Clinical Outcomes Associated with Blood Culture Contamination, Evaluation of Hospital Blood Culture Utilization Rates to Identify Opportunities for Diagnostic Stewardship, Impact of Antimicrobial Stewardship Program on Hospital Acquired Candidemia, Association Between Time to Appropriate Antimicrobial Treatment and 30-day Mortality in Patients with Bloodstream Infections, Polio Declared State of Emergency for New York, Trends in Parents’ Confidence in Childhood Vaccines During Pandemic, Severe Respiratory Illnesses Associated with Rhinoviruses and/or Enteroviruses Including EV-D68 – Multistate, 2022; Monkeypox: Presenting as Proctitis in Men Who Have Sex with Men, Single and 2-dose Vaccinations with MVA-BN® Induce Durable B Cell Memory Responses in Healthy Volunteers Comparable to Older Generation Replicating Smallpox Vaccines, Two Cases of Monkeypox-Associated Encephalomyelitis, LA County Man Died from Monkeypox, Guidance for Tecovirimat Use Under Expanded Access Investigational New Drug Protocol during 2022 U.S. Outbreak, FDA Warns Monkeypox Virus May Develop Resistance to Tecovirimat, Case Trends in US, HIV and Sexually Transmitted Infections Among Persons With Monkeypox; COVID: Updates, The Lancet Commission on Lessons for Future Pandemic, Association Between BNT162b2 Vaccination and Reported Incidence of Post-COVID Symptoms: Cross-Sectional Study 2020-21, Israel, Mortality Risk Among Patients Hospitalized Primarily for COVID During Omicron and Delta Variant Pandemic Periods, Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, Resistance of SARS-Cov-2 Omicron Subvariant BA.4.6 to Antibody Neutralization, Effect of Test-and-Treat Approach to Vitamin D Supplementation on Risk of All Cause Acute Respiratory Tract Infection and COVID: Phase 3 Randomised Controlled Trial (CORONAVIT), Detection of Higher Cycle Threshold Values in Culturable SARS-Cov-2 Omicron BA.1 Sublineage Compared With Pre-Omicron Variant Specimens, Antibody from Single Human VH-Rearranging Mouse Neutralizes All SARS-Cov-2 Variants Through BA.5 by Inhibiting Membrane Fusion, Vaccines in Infants, Children, and Adolescents, Effectiveness and Durability of BNT162b2 Vaccine Against Omicron Sublineages in South Africa

September 18, 2022

Association of Facility-Level Antibiotic Use and Hospital-Onset Clostridioides Difficile Infection in U.S. Acute-Care Hospitals; Fit-Tested N95 Masks Combined With Portable High-Efficiency Particulate Air Filtration Can Protect Against High Aerosolized Viral Loads Over Prolonged Periods at Close Range; Impact of Pneumococcal Conjugate Vaccines on Antibiotic-Nonsusceptible Invasive Pneumococcal Disease in the U.S.; Swine Influenza; Monkeypox by numbers; COVID-19: Variant BA.4.6; Covid by the numbers; FDA/CDC Approval Bivalent Vaccine; COVID-19 Journal Review: Immunity, Variants, Boosters; Early Treatment of Favipiravir in Patients Without Pneumonia: A Multicentre, Open Labelled, Randomized Control Study; Risk of BA.5 Infection Among Persons Exposed to Previous SARS-CoV-2 Variants

September 5, 2022

Ultra-Short-Course Antibiotics for Suspected Pneumonia With Preserved Oxygenation, Short-Course Antibiotic Therapy for Hospitalised Patients with Early Clinical Response in Community-Acquired Pneumonia: A Multicentre Cohort Study, Efficacy of Doxycycline for Mild-to-Moderate Community Acquired Pneumonia in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials, Two-Day vs Seven-Day Course of Levofloxacin in Acute COPD Exacerbation: A Randomized Controlled Trial, CDCRreorganization; Monkeypox: FDA Alert Regarding Fecal Microbiota Transplants, Monkeypox by Numbers, High-Contact Object and Surface Contamination in a Household of Persons with Monkeypox Virus Infection — Utah, June 2022, Environmental Persistence of Monkeypox Virus on Surfaces in Household of Person with Travel-Associated Infection, Dallas, TX, Clinical Features and Novel Presentations of Human Monkeypox - London Centre; Covid-19: FDA Authorizes Emergency Use for Novavax for Ages 12-17; Moderna Sues Pfizer and BioNTech; Pfizer and Moderna Files for Emergency Use of BA.4/BA.5 Omicron Booster, Omicron Subvariant BA.2.75, Covid Hospitalization by Age, Covid by Numbers, Test-to-Stay (TTS) After SARS-CoV-2 Exposure: A Mitigation Strategy for Optionally Masked K-12 Schools, Durability of Heterologous and Homologous Vaccine Boosts, Randomized Trial of Metformin, Ivermectin, and Fluvoxamine, Oral Nirmatrelvir and Ritonavir in Non-Hospitalized Vaccinated Patients, Nirmatrelvir Use and Severe Outcomes During Omicron Surge, Real-World Effectiveness of Early Molnupiravir or Nirmatrelvir– Ritonavir in Hospitalised Patients Without Supplemental Oxygen, Requirement on Admission During Hong Kong’s Omicron BA.2 Wave: A Retrospective Cohort Study, Safety Monitoring of Pfizer-BioNTech Vaccine Booster Among Children Aged 5–11 Years — United States, May 17–July 31, 2022, Incubation Period Caused by Unique SARS-CoV-2 Strains A Systematic Review and Meta-Analysis, Risk for Myocardial Infarction, Stroke, and Pulmonary Embolism Following Vaccines in Adults Younger Than 75 Years in France

August 29, 2022

Antibiotic Resistant Infections in Covid-19 Inpatients; New Zoonotic Henipavirus in China; Polio in New York City Wastewater; Monkeypox: Monkeypox by numbers; FDA Grants EUA for Jynneos Vaccine Intradermally; Human to Dog Transmission of MPXV; Asymptomatic MPXV; MPXV Isolation in Semen; COVID-19: New CDC Guidance; Covid by Numbers; Novavax Applies for Booster; UK Approves Two-Strain Vaccine; MMWR Summary on CDC Updated Guidance; Use of RAT to Screen for SARS-CoV-2; Health care Utilization After Covid

August 17, 2022

Impact of Antibiotics on Gut Microbiome and Resistome in Healthy Adults; CRE in Persons with/without Risk Factors; Antibiotic Use in Hospice and Palliative Care; Proposed AMR Registry; Environmental Contamination with B. Pseudomallei; Polio Detection in Wastewater Surveillance in NY; Monkeypox: CDC Makes It a Reportable Disease; US Declares National Health Emergency; Cases by Numbers; Tecovirimat Treatment Considerations; COVID-19: Impact on US Health; Covid by Numbers; Impact on Adolescent Mental Health; Association Between Vaccination and AMI and Stroke; Oral Vaccination; Intranasal Vaccine; Baricitinib Meta-Analysis; Relapse After Nirmatrelvir/Ritonavir; Resistant Mutation after Sotrovimab; Duration of Yymptoms and Association with +RAT After Infections with SARS-CoV-2

August 8, 2022

Impact of Covid-91 on AR; AHRQ Project on Improving Antimicrobial Prescribing; Possible Role of Adenovirus and Acute Hepatitis; Use of High Dose or Adjuvant Influenza Vaccine in Seniors; Polio in Unvaccinated Person in US; Initial Response to Monkeypox in US; WHO Declared Monkeypox a Global Health Emergency; Monkeypox Cases in Several Countries; Update on Tecovirimat; European Centre for Disease Prevention and Control (ECDC) and European Medicines Agency (EMA) Recommendations for People 60-79 YOA and High Risk Individuals; FDA/CDC Approval of Novavax; IDSA Update on Ivermectin; Covid by Numbers; Seroconversion and Outcomes after Initial and Booster Vaccinations in Adults with Hematologic Malignancies; Airborne Transmission of SARS-CoV-2; VE of 2, 3, and 4 Covid-19 mRNA Vaccine Doses Among Immunocompetent Adults

July 23, 2022

Variability in Prescribing Empiric Gram-Negative Antibiotics, Trends in Antimicrobial Prescribing for Patients with Possible Sepsis, Monkeypox Update, Phylogenomic Characteristics in the 2022 Outbreaks; Covid-19: FDA Authorizes Pharmacists to Prescribe Paxlovid, Omicron mutation BA.2.75, Covid by Numbers, Use of Oral Sabizabulin for High-Risk Hospitalized Patients, Leading Causes of Death in US, Outcomes in Patients with SARS-CoV-2 Reinfections, Covid Related Croup

July 11, 2022

Update on HAIs During Second Year of Covid-19, Prevalence of Inoculum Size and Cefazolin Susceptibility Against MSSA, Effect of Vitamin C in Adults with Sepsis, Monkeypox Update; Covid-19: FDA Approval of Updated Vaccine to Include Omicron Component, Covid by the Numbers, Subvariant Update, Commonwealth Report Highlighting Needs to Meet Future Public Health Challenges and a Companion Piece to this Report, Evaluation of Long Covid by Variant, Effectiveness of Paxlovid, Immune Escape of New Omicron Variants

July 4, 2022

Risk of Vertical Transmission of HCV, Challenges of Defining Optimal Therapy for Persistent MRSA Bacteremia, Monkeypox Update and Mixed Messaging from CDC; Covid-19: CDC has Dropped Testing to Return to US, FDA Advisory Committee Recommended EUA for Novavax Vaccine, Updates of Variants, Covid by Numbers, Moderna Announced Results of Bivalent Booster, Upcoming FDA Meetings, Study Looking at Use of Evusheld for Early Treatment, Examination of Humeral and Cellular Immune Memory 4 Vaccines, GI Symptoms and Fecal Shedding of SARS-CoV-2 RNA, Risk of MIS-C During Omicron Surge

June 20, 2022

Overuse and Misuse of Antibiotics Prescribed for Pediatric URIs and ABU in Adults, Global Comparison of Prevalence and Trends of GI Colonization of ESBL-E coli, Impact of Increased Carbapenemases Testing at the National VA, Monkeypox Update; Covid-19: Update of Novavax FDA Application, Impact of Omicron on Deaths in Older Adults, IDSA Guidelines Updates, Covid by Numbers, Post-Covid Conditions in Adult Survivors, Paxlovid Outcomes During the Omicron Surge, Antibody Duration in People Infected with SARS-Cov-2

June 6, 2022

Impact of Macrolides on Mortality of Bacteremic Pneumococcal Pneumonia, Summary of Monkeypox, Infection Prevention of HAIs and Impact of Covid-19, Influenza Update; COVID-19: Current State of the Pandemic and Recommendations, FDA Action on EUA Application on Fluvoxamine, CDC Update on Guidance for Domestic Travel, Pfizer Vaccine Results for Young Children, CDC HAN Release on Rebound after Paxlovid, Covid by the Numbers, Omicron Breakthrough Infections and Neutralizing and Memory B Cell Responses, Long Covid and Impact of Vaccination, Severity and Incidence of MIS-C During Last 3 Waves Including Omicron, Longitudinal Sequalae, Immunity, and Laboratory Evaluation After Infection, VE of 4th Dose Comparted to 3 Doses, Protection and Duration of Natural and Hybrid Immunity After infection.

May 31, 2022

C. diff at Home After Recent Hospital Discharge, ASP on Discharge; Covid-19: CDC Continues to Recommend Masks on Public Transportation and Planes, Updates on Variants, Covid by the Numbers, FDA Limits Authorized Use of J&J Vaccine Further, Sobering Numbers of Deaths in the US, Review of OP Treatment Options, FDA Authorized Pfizer Booster for Children 5-11, FDA Approves New Indication for Baricitinib, Maternal and Infant Outcomes with Covid, Comparative Effectiveness Over Time of the Moderna and Pfizer Vaccines, Final Results of Solidarity RDV and Meta-Analyses of Mortality in Relevant Trials to Date, Treatment with Baricitinib and IL-6 Inhibitors, SARS-CoV-2 Transmission from Air vs Surfaces, Two New Vaccines.

May 16, 2022

Environmental Shedding of C Difficile Based on Treatment Administered, J-Curve Relationship Between Time-to-Antibiotics and Outcomes in Patients Admitted with Bacterial Infection; Covid-19: FDA Approved RDV for Treatment in Children, Updates on FDA Vaccine Reviews, Pfizer Announced the Failure of Nirmatrelvir/Ritonavir to Meet Primary Goal on Reducing the Risk of Infection in Adults, Covid by Numbers, CDC Report on Seroprevalence, Rapid Relapse After Nirmatrelvir/Ritonavir Treatment, Durability of Pfizer Vaccination Against Hospitalization, Update from the WHO on Covid Drugs, CDC Reports on Hospitalizations of Children Aged 5-11 During Omicron, Comparison of Home Antigen Testing with PCR and Viral Culture, Longitudinal Sampling of SARS-CoV-2

May 2, 2022

Discussion of Cefiderocol; Covid-19: Annual Rate of Hospitalizations for RSV, Influenza, and Covid in Children, APKFF Tracker on Causes of Death and Deaths Prevented by Vaccination, CDC/APIC Meeting Highlights, IDSA Response on Lifted Mask Mandate, Covid by the Numbers, Effectiveness of mRNA Vaccines in Healthcare Workers, Meta-Analysis and Review on Long Covid, Effectiveness of Evusheld in Immunocompromised Population, Incidence of Myocarditis in Scandinavia, Rates of Infection in Unvaccinated Adults with Natural Immunity, Impact of Masks and Social Distancing on Risk of Transmission in One-to-One Exposures

April 25, 2022

Commentary on Boosters; Gram Stain in Treatment in Patients with VAP, Outpatient Antibiotics in Medicare Patients during First Year of Covid-19, Duration of Antimicrobial Prophylaxis and Risk of SSIs, Incidence of Ocular Complication in Patients with Candidemia; Covid-19: Sabizabulin in Preventing Deaths, FDA Granted EUA to Breathalyzer Test, Pfizer Study on Boosters and Immune response in Children, Covid by the Numbers, VL in Unvaccinated and Vaccinated Individuals, Meta-Analysis on Use of Fluvoxamine in Preventing Progression Patients; Postmortem Assessment of Olfactory Tissue in Patients, Review of Myopericarditis Following Vaccination and Non-Covid Vaccination

April 18, 2022

Baloxavir vs. Oseltamivir in Reducing Family Transmission; Short vs. Standard Duration for Outpatient Therapy for CAP in Children; COVID-19: Withdrawal of Sotrovimab Since BA.2 Over 50% of Circulating Strains in the US, White House Announces National Plan to Fight Long Covid, UK Report on New Combo Variant EX, Brief FDA Vaccine Advisory Committee Meeting Synopsis, ECDC and EMA Weigh in on Second Booster, Covid by the Numbers, Impact of Discontinuing Atorvastatin in Patients Admitted with Covid, Pandemic Impact on Mental Health, Single vs. Repeat Rapid Antigen Testing Among Asymptomatic Individuals, Test-to-Stay Successful in Keeping Classrooms Open Safely, Incidence and Outcomes with Delta and Omicron in Children Under 5, Israel Reports on Second Booster Against Omicron, Natural Immunity vs. Vaccination and Hybrid Immunity and Reinfection and/or Breakthrough Infection

April 11, 2022

Use of Single Dose Liposomal Amphotericin B for Cryptococcal Meningitis; Antimicrobial Susceptibility of Invasive N Meningitis in the US; Updated Recommendation for Universal Hepatitis B Vaccination in Adults Aged 19-59; COVID-19: FDA Authorization for Second Booster, Covid-19 by the Numbers, Use of Second Booster to Reduce Mortality in Older Adults, Impact of Pfizer Vaccination Against Omicron in Children, Peer Reviewed Publication of Use of Ivermectin for Early Treatment, Early Treatment with Convalescent Plasma, Use of Rapid Antigen Test After Acute SARS-CoV-2 Infection for the Purpose of Returning to Work Safely

April 4, 2022

Use of Methenamine in the Treatment of Recurrent UTIs in Women; Issue of Combination Therapy for MDR-Pseudomonas aeruginosa; COVID-19: Moderna Reports Initial Results on Low-Dose Covid Vaccine in Children Under 6, FDA Considering Second Booster for Adults, Activity of Sotrovimab Against BA.2, CDC Update, Clear Benefit of Vaccination in Pregnancy, Duration of Virus Shedding in Patients Infected with Omicron Variant, Real World Experience of Breakthrough Infection Resulting in Hospitalization After Vaccination Versus Natural Infection, Effectiveness of mRNA Vaccination in Preventing Mechanical Ventilation and Death

March 28, 2022

ABATE Infection Toolkit is Now Live on the AHRQ Website

March 24, 2022

Stepped wedge cluster control trial using clinical decision support for patients with CAP admitted through the ED; Development of antibodies to C. diff infection & risk for recurrence; Summary of ECRI top patient safety concerns for 2022; Covid-19 by the numbers and updated variant report; Will Covid-19 cases start to rise again in the US?; Presentation to NIH on ivermectin; IDSA’s update on use of inhaled steroids for ambulatory patients with mild-to-moderate Covid-19; Report on Deltacron, followed by evaluation of neutralizing antibodies against BA.1 and BA.2; Recommendation from ACIP addressing extending the dosing interval for primary series for mRNA vaccines; Risk of myocarditis after third dose with Pfizer vaccine in military recruits; Effect of Sotrovimab on hospitalization & deaths for high-risk patients with mild-to-moderate Covid-19; CDC report on hospitalizations of infants & children aged 0-4 years infected with SARS-CoV-2; VE of a fourth dose of an mRNA vaccine against Omicron

March 21, 2022

Use of new MCA with long half-life appears more effective than palivizumab; Shorter treatment for select children & adults with drug-susceptible TB; Influenza update & report on VE of current influenza vaccine this season; Announcement on “A Roadmap for Living with Covid;” Reversal from WHO on booster shots; Update on Covid-19 by the Numbers; Incidence of Covid-19 among 6th-12th grade students by vaccination status; CDC report on Omicron transmission within households; Structural brain changes & cognitive changes in Covid-19 survivors; Hospitalization & mortality among Medicare beneficiaries in non-SARS-CoV-2 admissions; Antiviral agents (MCA & antivirals) against BA.2; Comparison of incidence of Covid-19 in schools districts with mask-required vs. mask-optional policies

March 14, 2022

RSV mortality in infants & elderly; Etiology, treatment, outcomes in patients with severe CAP; Impact of S pneumoniae urinary antigen in patients admitted with CAP; Key elements of the White Plan for Covid-19; NIH treatment update on bebtelovimab; Weekly update on Covid-19 by the Numbers; List of FDA approved at-home OTC-Covid-19 tests; VE of Pfizer vaccine among children ages 5-17; VE of several vaccines against Omicron in the UK; Updated meta-analysis on RDV; RECOVERY trial on baricitinib; Surveillance of SARS-CoV-2 in environmental & animal samples from Wuhan market; Cause of Covid-19 induced anosmia.

March 7, 2022

Blood Culture Stewardship; Epidemiology and Microbiology on HAP; Covid-19: second booster, the application for the Sanofi Glaxo Covid-19 vaccine, the dosing change to Evusheld, a BA.2 update, and Covid-19 by the numbers, BA.1 infection followed by BA.2 reinfection, highlight T and B cell and cross immunity, population immunity and Omicron severity in South Africa, hospitalizations of children from July 2021-January 2022, antigen test positivity after Covid-19 isolation/infection.

February 28, 2022

Open Letter Public Health Professionals Urge Elected Officials to Reevaluate the End of School Mask Mandates

February 26, 2022

Dr. Ed’s Perspective and Commentary

View Open Letter

Recommended Adult Immunization Schedule, United States, 2022; EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge; Strategies for Antibiotic Administration for Bowel Preparation Among Patients Undergoing Elective Colorectal Surgery A Network Meta-analysis; Attributable Mortality of Candida Bloodstream Infections in the Modern Era: A Propensity Score Analysis; COVID-19 News CDC Announces Voluntary COVID Rules for Cruises; Novavax; COVID-19 by the Numbers; As Omicron Surged, Covid-19 Spread Through Patients in Hospitals; and more

February 21, 2022

Faecal microbiota transplantation reduces amounts of antibiotic resistance genes in patients with multidrug-resistant organisms; Multicenter Cohort Study of Ceftaroline versus Daptomycin for Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infection; US Considers Lengthening Gap Between First 2 COVID Shots to 8 Weeks; COVID-19 vaccine for kids under 5 delayed; FDA Authorizes New MCA, Bebtelovimab for Treatment of COVID-19; DSA Convalescent Plasma Guideline Update January 31, 2022; Vaccines Elicit Highly Conserved Cellular Immunity to SARS-CoV-2 Omicron; Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome; Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications; Characteristics, Outcomes, and Severity Risk Factors Associated With SARS- CoV-2 Infection Among Children in the US National COVID Cohort Collaborative; Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection; High Rates of Rapid Antigen Test Positivity After 5 days of Isolation for COVID-19; Initial analysis of viral dynamics and circulating viral variants during the mRNA- 1273 Phase 3 COVE trial; Protection against the Omicron Variant from Previous SARS-CoV-2 Infection; Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19– Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022

February 14 2022

Outpatient Stewardship; Connection Between Hospital Antibiotic Exposure and the Potential of MDROs; COVID-19: FDSA Full Approval for Individuals 18 and Up, Pfizer Application for Vaccination in Children <5, Novavax Applied for EUA for Protein-Based Vaccine, COVID by the Numbers, Influenza Update, Johns Hopkins Meta-Analysis on the Impact of Lockdowns, Non-Pharmaceutical Interventions on Pediatric Hospitalization for Other Respiratory Infections, Correlation Between Country's Mistrust and Infection Rates, Impact of Natural Immunity and Infection, Difference of BA.1 and BA.2, Impact of Moderna Booster, Infections and Hospitalizations in LA Before and During Omicron, Effectiveness of Masks in a Real World Setting

February 7, 2022

Perspective on COVID Policies and Pivoting; Global Burden of Antimicrobial Resistance; SHAE Journal on Outpatient Antibiotic Prescribing; COVID-19: Review on Omicron, FDA Action on Suspending Two Monoclonal Antibodies and Approval of Remdesivir for Outpatient Treatment, COVID by the Numbers, Trends in Severity and Healthcare Utilization with Omicron, Hospitalizations by Vaccination Status and Prior Infection, Early Assessment of Omicron on Severity in South Africa, Omicron Dynamics in the UK, Early Factors that May Contribute to Long COVID

January 30, 2022

Impact of HA-BSIs on Mortality; Using Adult Sepsis Definition to Identify HAIs; Exciting Oral Microbiome to Treat rCDI; COVID-19: Preliminary Data on Administering a 4th Shot, Symptoms of Omicron vs. Delta, Summary of the Center for Strategic and International Studies Commission on Improving Health Security, Figures on Incubation, Viral Loads, Testing, and New Isolation Guidelines, Medscape Survey on Burnout and Depression, Weekly COVID Numbers Update, US Influenza Report, Estimating Infections, Hospitalizations, and Deaths Following Vaccination, Risk of Infection in Breast Milk, Effectiveness of a 3rd Dose of mRNA Against ED and Urgent Care Visits and Hospitalizations for Delta and Omicron, Environmental Contamination with SARS-CoV-2, Experience with Wastewater Surveillance in US, Canadian Experience with RDV

January 24, 2022

Perspective on COVID in 2022; Emergence of C. diff. Isolates with Decreased Susceptibility to Vancomycin; Expert Panel Review on Optimal Urine Culture Diagnostic Stewardship; Effect of 7 vs 14 Days of Antibiotic Treatment in Men with Afebrile UTIs; COVID-19: NIH Chart Comparing Cold, Flu, Allergy, COVID, CVDC Update on Masks, Updated COVID Numbers, Outcomes Among Patients Infected with Omicron, Impact of Third Dose of Pfizer in HCW in Israel, Asymptomatic Rate Associated with Omicron, Direct Comparison of PCR Tests vs Rapid Antigen Tests During Omicron Surge, Vaccine Efficacy of Pfizer in Adolescents, Duration of Vaccine Efficacy For Symptomatic Disease and Severe Disease and Death, Impact of Infection During Pregnancy

January 17, 2022

Assessment and Control of C auris in Orange County; Consensus Guidance on Management of GN-BSIs; COVID-19: FDA Action on Boosters, NIH Guidelines, CDC Adding "Up to Date" Definition of Vaccination, Preliminary Second Booster Data from Israel, Overview of Isolation and Quarantine for K-12 Students, Numbers Update, South African Report on Outcomes of Patients Admitted with Omicron, Household Transmission of Delta vs. Omicron, Impact of Vaccination on Transmission Between Alpha and Delta, Review of Rapid Diagnostic Testing, Risk Factors for Severe Outcomes Among Vaccinated Persons, Initial Houston Experience with Omicron, Association Between Menstrual Cycle and Vaccination, Risk of Newly Diagnosed Diabetes and COVID in Children, Effectiveness of Vaccination Preventing MIS-C

January 10, 2022

General Interest Articles on Sepsis and MRSA Bacteremia; COVID-19: by the Numbers and When Omicron Might Peak, December 31 UK Technical Briefing, CDC Guidelines on Quarantine and Isolation, FDA Considering Booster Dose Recommendation for 12-15-Year-Olds, Sensitivity of Rapid Antigen Testing, South African Experience During Omicron Wave vs Previous Waves, Animal Models Demonstrate Lower Replication of Omicron in the Lung, T-Cell Responses via Vaccine or Infection Against Omicron, Safety of Pfizer Vaccine in Children 5-11, Clinical Outcomes of Hospitalized Children Aged <18

January 2, 2022

COVID-19 – New CDC Guidance

December 28, 2021

COVID-19 – Oral Antivirals, Novavax Vaccine Shows Promise Against Omicron, South Africa Ending Quarantines and Contact Tracing, Summary of December 23 UK Technical Briefing, Testing Guidance Amid Test Shortages, Current COVID Numbers, Viral Dynamics in Vaccinated vs Unvaccinated Individuals, Outbreak in Norway, Impact of Pfizer Booster in Israel, Use of Remdesivir to Prevent Disease Progression in Outpatients

December 26, 2021

COVID-19 – Revised CDC Guidance

December 24, 2021

COVID-19 – Taking the Fear Out of Omicron, Omicron in the US, CDC Guidance on Testing Before the Holidays, Latest Death Numbers in the US, Europe Approves Novavax Vaccine, Uptick in Influenza Numbers, Variant Cross Neutralization After Breakthrough Infection, Risk of Myocarditis Between Moderna and Pfizer Vaccines, Molnupiravir Activity, Convalescent Plasma in the Outpatient Setting

December 22, 2021

December 22 Special Update: FDA Issues EUA for Paxlovid, Hospitalization Risk with Omicron Significantly Lower

COVID-19 – What We Know About Omicron and Steps to Reduce Infections, Current Numbers as of Last Week, Preliminary Report on Christmas Party Outbreak in Oslo Restaurant, Disappointing Pfizer Data on Vaccine Trial of Children Under Five, Test-to-Stay Strategy in Schools K-12, Encouraging Data from AstraZeneca's Monoclonal Antibodies, CDC States Preference for mRNA Vaccines, Moderna Booster Dose Facilitates Efficacy Against Omicron, Real World Data on Test-to-Stay from Two Counties

December 20, 2021

COVID-19 – Perspective and Reflections and Paxlovid, Pfizer Vaccine Activity Against Omicron, Lung Model Comparing Omicron to Other Strains, Effectiveness of Pfizer Vaccine Against Omicron in the UK, Use of Portable HEPA/UV Removal of Bioaerosols, Novavax Vaccine Efficacy, Difference in Risk of Transmission Between Fully Vaccinated Persons and Unvaccinated Persons, Up to 40% of Infected Persons May Be Asymptomatic

December 16, 2021

COVID-19 – FDA Issues Emergency Use Authorization for AstraZeneca Monoclonal Antibodies, Update on US Deaths, Commentary on Origin of Omicron Mutation, Outcomes of Pregnancy in Vaccinated Versus Unvaccinated Individuals, Possible Explanation of Correlation Between Obesity and More Severe Disease, Emotional Impact of the Pandemic on Healthcare Providers

December 13, 2021

COVID-19 – Pfizer Booster May Provide Better Protection Against Omicron, FDA Approves AstraZeneca Monoclonal Antibody Therapy for Emergency Use, EMA Recommendations on Heterologous Vaccination Courses, Heterologous Vaccination Details, Genetic Analysis of Omicron and Common Cold Viruses, Impact of Booster Dose in Israel and Mortality, Safety and Immunogenicity of Seven Vaccines as a Third Dose

December 9, 2021

COVID-19 – Molnupiravir Authorization Narrowly Recommended by FDA Advisors, CDC Recommends Boosters to All Adults in Light of Omicron

December 1, 2021

Special COVID-19 Update: Omicron Variant - What We Know; Updated Molnupiravir Data

November 27, 2021

COVID-19 – France Advises Against Moderna Vaccine for People Under 30, Regeneron Monoclonal Antibodies Reduces Risk of Contracting the Disease by 81.6%, Coronaviruses in Bats and Deer, Lactating Parents and Pattern of IgA and IgG Antibodies in Human Milk Between Infection and mRNA Vaccination, Pfizer Vaccine Phase 2/3 Trial in Children 5-11

November 12, 2021

COVID-19 – Press Release on Pfizer Oral Antiviral, Population-Based Cohort Study on CVST Incidence Rate After J&J Vaccine, Vaccine Efficacy in US Veterans for All 3 Vaccines Over Time, Analysis of the J&J Vaccine

November 9, 2021

COVID-19 – Global Death Toll, CDC Approves Pfizer Vaccine for Children 5-11, UK Approves Molnupiravir, WHO Approves Indian Vaccine, Primary and Secondary Immune Responses, Vaccination After Infection Can Stimulate Memory B Cell Response, Prior Infection Associated with Lower Risk of Breakthrough Infection After Vaccination, Durability of Antibody Levels After Vaccination, Third Dose of Pfizer Vaccine Highly Effective at Protecting Individuals Against Severe Outcomes Compared with Only Two Doses

November 5, 2021

COVID-19 – Hybrid Immunity and Current US Policy, CDC Report on Breakthrough Cases, Formal FDA Approval for Pfizer Vaccine for Children Ages 5-11, Delay in Approving Moderna Vaccine in Ages 12-17, IDSA Update on Fluvoxamine, CDC Publication on Hospitalized Adults with Infection-Induced Versus Vaccine-Induced Immunity, Community Transmission and Viral Load Kinetics of the Delta Variant in Vaccinated and Unvaccinated Individuals, Managing Vaccination in Persons with Allergies

November 2, 2021

COVID-19 – FDA Panel Deliberation for Pfizer Application for Approval in Children 5-11, CDC Update on Boosters for Immunocompromised Persons, Fluvoxamine Use for Early Infections in Persons with Known Risk Factors, Use of Sotrovimab for Early Infections in Persons with Risk of Severe Disease, Mortality Rates in the General Population of Vaccinated and Unvaccinated Persons

October 29, 2021

COVID-19 – New Descendent Related to Delta, Pfizer Vaccine Efficacy in Children 5-11, CDC Pandemic Update, CDC Report on Severity from January through August, Dexamethasone Doses of 6 mg Versus 12 mg, A Retrospective Comparative Effectiveness Cohort Study on Remdesivir

October 26, 2021

COVID-19 – FDA and ACIP Meetings on Boosters, Vaccine Rollout for Children Ages 5-11, Communication Strategies for Vaccines, Pfizer Vaccine Efficacy in Adolescents, Vaccine Efficacy in Preventing Deaths in Pfizer and Astrazeneca

October 22, 2021

COVID-19 – VRBPAC Recommends Second J&J Dose, FDA Currently Reviewing mRNA Vaccine Myocarditis Risk and Mixing Vaccine Variations, Revised CDC Holiday Guidance, Updated IDSA Guidance for Baricitinib, Natural Immunity vs. Vaccine Immunity, COVID-19 Hospital Prevalence as a Risk Factor for Mortality, Support for Masking as an NPI to Reduce Transmission

October 19, 2021

COVID-19 – Use of Monoclonal Antibodies in Select Hospitalized Patients, Tuberculosis Deaths on the Rise Again Due to COVID-19, FDA Panel Approval of Half-Dose of Moderna as a Booster, Evaluating Homologous and Heterologous Booster Vaccinations, Pandemic-Related Depression and Anxiety Disorders

October 15, 2021

COVID-19 – CDC Update on Pandemic in the US, Merck has Applied for EUA for Molnupiravir, Research on Immunity Through the ZOE App, Immunity in Vaccinated Versus Unvaccinated Convalescent Individuals, Incidence of Primary Infection and Reinfection During Pandemic First Wave, Household Infection Risks Within Prospective Household Cohort, Virulence of the Delta Variant, Symptoms One Year After Natural Infection

October 12, 2021

COVID-19 – EMA Approves Pfizer Booster for Those 18 and Older, AstraZeneca Seeks FDA Approval for Preventative Antibody Treatment, Pfizer Application Submitted to FDA for Vaccine in Ages 5-11, Myocarditis and mRNA Vaccines, Waning Immunity Associated with Pfizer Vaccine

October 8, 2021

COVID-19 – Molnupiravir Update, Update on Rates, Hospitalizations, and Deaths, Impact of Boosters in Older Adults in Israel, FDA Announcement on Upcoming Hearings, Vaccine Efficacy in Adolescents, Report on Third Dose Side Effects, Model of Predictive Symptoms of COVID-19

October 5, 2021

COVID-19 – Preliminary Result in Pfizer Phase 2/3 Trial in Children 5-11, Latest Number of Pediatric Cases in US, Kaiser Foundation Update on Vaccine Dashboard, Remdesivir Efficacy Press Release, Remdesivir Plus Standard of Care, Impact of Remdesivir Based on Pre-Admission Symptom Duration, Efficacy of Monoclonal Antibodies in Outpatient Setting, Maternal-Neonatal Transfer of SARS CoV-2 IgG Antibodies

October 1, 2021

COVID-19 – Reflections on Vaccine/Booster Conversation, Death Toll from COVID Surpasses 1918 Pandemic, Impact of Masking in K-12 Schools, Impact of Routinely Testing Students and Staff

September 28, 2021

COVID-19 – J&J Second Dose Response, Mixed Messaging from CDC, ACIP, and Dr. Walensky, Real-World Effectiveness of the Vaccines at Preventing Symptomatic Illness in Healthcare Workers, Use of Steroids in Non-Oxygen Dependent COVID-19 Patients, Delirium in COVID-19 Patients Admitted to the ICU

September 24, 2021

COVID-19 – Revised EUA for Bamlanivimab and Etesevimab to Include Emergency Use as Post-Exposure Prophylaxis, FDA Advisory Board on Boosters, CDC to Distribute $2.1 Billion to Boost Nation's Infection Control and Prevention Efforts, Pfizer Announcement on Vaccinating Children Ages 5-11, Vaccine Efficacy of Three Vaccines in Preventing Hospitalization, Study on "Test-to-Stay" Policy as Quarantine Alternative for Exposed Students, Percentage of Completed Vaccinations Among Nursing Home Residents and Different Staff Types

September 21, 2021

COVID-19 – UK Approves Third Shot for Persons Over 50, Demonstrated Potential Benefits of Booster Doses in Persons who Received the Pfizer Vaccine, Effect of Vaccination on Household Transmission of SARS-CoV-2, Potential Value of Wastewater Surveillance in Public Health, Efficacy of Masks Based on COVID-19+ Case-Patients Paired Breath Samples

September 17, 2021

COVID-19 – Patients Can Now Receive COVID Vaccine and Flu Vaccine During Same Visit, Further Vaccine Effectiveness Studies, Natural Immunity Versus Vaccine-Induced Immunity, Evidence for Booster Dose Recommendations

September 15, 2021

COVID-19 – State of the Pandemic in the US, President's Vaccine Initiative, Mu Update, CDC Reports on Hospitalizations and Emergency Department Visits Among Children and Adolescents, Animal Model on Use of Molnupiravir and Potential Use of Fluvoxamine and the Ongoing Controversy of Ivermectin, Potential Benefit of JAK Inhibitors for Select Patients with Severe Disease

September 10, 2021

COVID-19 – Vaccine Safety Surveillance, Vaccine Effectiveness in Highly Vaccinated Health Care Workers, Breakthrough Infections in Vaccinated Health Care Workers and Correlation with Neutralizing Antibody Titers, Impact of COVID-19 and Hospital-Acquired Infections, SARS-CoV-2 Seroprevalence Increasing Over Time

September 6, 2021

COVID-19 – Commentary on ACIP/FDA Recommendations and Shared Community Goals, CDC Guidance on Labor Day and Start of School, Most Recent WHO Report, Update on Mu Variant, Waning Antibody Protection in Pfizer Vaccine vs Natural Immunity, Increased Vaccine Interval Results in Increased Antibody Titers After Second Dose, Risk of Long COVID Reduced in Fully Vaccinated Individuals, Casirivimab-Imdevimab Treatment in Mild to Moderate COVID-19 Associated with Decrease in Rate of Hospitalization

September 3, 2021

COVID-19 – ACIP Meeting Report, UK vs US in Vaccinations and Deaths in Persons >65, Data Driven Model Estimates Infection Numbers Pre-Delta, More Evidence Delta May Cause More Severe Illness than Other Varieties with Higher Hospitalization Rates, Israel Prepublication on Impact of Booster Vaccine Dose, Elementary School Outbreak with Delta Variant, Antibody Response Between Pfizer and Moderna Vaccines,

August 31, 2021

COVID-19 – Preliminary Report from J&J on Booster Doses, Improper Use of Ivermectin Including Formulations Not Intended for Human Consumption and Adverse Events, Weekly Report from AAP on Pediatric Cases and Hospitalizations, SARS-CoV-2 Infections by Vaccination Status, Vaccine Effectiveness Among Healthcare Workers During Delta Surge, Estimated US Deaths Averted Due to Vaccinations, Evaluation of Pfizer Vaccine Safety

August 27, 2021

COVID-19 – CDC/ACIP Meeting on General Population Booster Shots Postponed by a Week, Report on Pediatric Hospitalizations During Delta Surge, Pfizer Vaccine Receives Full FDA Approval, Virological Characteristics of Breakthrough Cases in Healthcare Workers, SARS-CoV-2 Dynamics in Close Contacts, Saliva PCR Compared to Nasopharyngeal PCR

August 24, 2021

COVID-19 – Small Correction from Tuesday, Discussion of Potential Third Vaccine Dose or Booster, Vaccine Effectiveness in Nursing Home Residents, Duration of mRNA Vaccine Effectiveness Against Hospitalization in Patients 18 and Older, Rates of New New York Infections and Hospitalizations by Vaccine Status, Convalescent Plasma in Outpatient Setting, Use of Hydroxychloroquine, Remdesivir, and Dexamethasone from Feb. 2020-Feb 2021

August 20, 2021

COVID-19 – Updated Numbers from the CDC, FDA/CDC/ACIP Recommendations for Administering Third Vaccine Dose for Immunosuppressed, Pfizer Filed for Clearance for Third Vaccine Dose for General Population, Moderna Results of Vaccinating Adolescents, Impact of COVID-19 on HAIs and MDROs, Report on Vaccinating HD Patients with Pfizer, Younger Children may be as Likely to Transmit SARS-CoV-2 Infection as Older Children

August 17, 2021

COVID-19 – Vaccine EUA Extended to Include Booster Dose for Certain Immunocompromised Individuals, Comparative Effectiveness of Both mRNA Vaccines During Alpha and Delta Prominence, Lambda Infectivity and Potential Immune Resistance, CDC Update on Reported Vaccine Adverse Events, Cochrane Review on Ivermectin for Preventing or Treating COVID-19

August 13, 2021

COVID-19 – Unvaccinated People may be Twice as Likely to be Reinfected than Those Vaccinated, Vaccine Effectiveness Among Household and Other Close Contacts, Illness Duration in Children Infected with SARS-CoV-2, Report on Myocarditis and Pericarditis Following mRNA Vaccines

August 10, 2021

COVID-19 – Updated Survey on Vaccine Hesitancy, FDA Expanded EUA for REGEN-COV, FDA Revised EUA for Baricitinib, Cape Cod Outbreak Overview and Commentary, Virological Kinetics of Delta Vaccine Breakthrough Infections, Census Bureau Vaccine Survey of US Households

August 3, 2021

COVID-19 – Impact of School Shutdowns, CDC Change in Testing Exposed Vaccinated Individuals, Israel to Offer Booster Vaccine Doses to Older and Immunocompromised People, Antibody Levels Remain High at Least 9 Months After Infection, Breakthrough Infections in Vaccinated HCWs, Use of Canakinumab in Patients with Severe Disease Not Requiring Mechanical Ventilation

July 30, 2021

Special Edition: COVID-19 – CDC Strengthens Mask Guidance, Guidance for Implementing Prevention Strategies with Varying Community Transmission Levels and Vaccination Coverage, CDC Science Brief on Vaccines and Vaccination

July 28, 2021

COVID-19 – ACIP Meeting on Third Dose Vaccine Booster for Immunocompromised Patients, COVID-19 Activity and New Hospitalized Cases by Age, Updated Recommendations for Fully Vaccinated People in Relation to the Immunocompromised, New Vaccine Mandates, Impact of Third Dose of mRNA Vaccine in Kidney Transplant Recipients, Statin and Anti-Hypertensive Drugs and Outcomes in Hospitalized Patients, Safety of Second mRNA Vaccine Dose in Patients with First Dose Reactions

July 27, 2021

COVID-19 – Mask Mandate Controversy Explained, Lambda Variant Update, AAP Guidance on Opening Schools in the Fall, Report on HCW Burnout, AHA Supports Mandatory HCW Vaccination, Evidence of Monoclonal Antibody Effectiveness in Outpatients, Nurse Staffing and Outcomes, Pfizer and AZ Vaccines Hold Up Well Against Delta for the Fully Vaccinated, J&J Vaccine Efficacy Against VOCs

July 23, 2021

COVID-19 – ACIP Meeting to Consider Vaccine Booster Doses, 2022 Deadline for mRNA Vaccine Full FDA Approval, Promising Antiviral Molnupirvar, CDC COVID-19 Update, Retraction from JAMA Pediatrics, Impact of COVID-19 Patient Caseload and Outcomes, Long Term Symptoms in Children Post COVID-19 Infection, More Negative Remdesivir Outcomes, Complications in Hospitalized Patients

July 20, 2021

COVID-19 – Current Scientific Consensus on Delta Variant, National Nurses United Union Sends CDC Letter Asking for Universal Masking to be Reinstated, More Advocates for Mandatory COVID-19 Vaccination for HCP, Viral Infection and Transmission in a Large Delta Variant Outbreak, Possible Relationship Between EBV Reactivation and Prolonged COVID-19 Symptoms

July 16, 2021

COVID-19 – CDC Guidance on Preventing COVID-19 in K-12 Schools, Discussion on Booster Doses, New GBS Warning Added to J&J Vaccine, Risk of COVID-19 in Children 18 Years and Younger, Importance of Second Shot in Protecting Against VOC, Vaccine-Related mRNA Not Detectable in Human Milk After Vaccination

July 13, 2021

VII Comments: Delta Update, Vaccinations, and Masking, Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 A Meta-analysis, Effectiveness and Harms of High-Flow Nasal Oxygen (HFNO) for Acute Respiratory Failure(ARF): An Evidence Report for a Clinical Guideline From the American College of Physicians, Appropriate Use of High-Flow Nasal Oxygen in Hospitalized Patients for Initial or Postextubation Management of Acute Respiratory Failure: A Clinical Guideline From the American College of Physicians, Persistent symptoms in adult patients one year after COVID-19: a prospective cohort study

July 9, 2021

CDC: 15M have missed their second dose, Sharp Declines in Breast and Cervical Cancer Screening, COVID-19 impact on screening test volume through the National Breast and Cervical Cancer early detection program(NBCCEDP), January–June 2020, in the United States, Ad26.COV2.S elicited neutralizing activity against Delta and other SARS‐CoV‐2 variants of concern, Frequency of Thrombocytopenia and Platelet Factor 4/Heparin Antibodies in Patients With Cerebral Venous Sinus Thrombosis Prior to the COVID-19 Pandemic, Patient and Hospital Factors Associated With Differences in Mortality Rates Among Black and White US Medicare Beneficiaries Hospitalized With COVID-19 Infection

July 6, 2021

The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Updated Emergency Use Authorization of the Anti-SARS-CoV-2 Monoclonal Antibody Combination Casirivimab Plus Imdevimab for the Treatment of COVID-19 , APIC Supports Mandatory COVID-19 Vaccine Policies in Healthcare Facilities, WHO versus CDC Mask Policy, Almost All US COVID-19 Deaths Now in the Unvaccinated, Delta Most Common Covid-19 Variant in U.S., Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine, AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC, Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines,

July 2, 2021

COVID-19 – Delta Update, FDA Granted Tocilizumab EUA for Treatment of Severe COVID-19, FDA Paused Distribution of Lilly Monoclonals, Incidence of Bell's Palsy with Vaccination, Impact of First Dose of AZ or Pfizer in LTC, First Dose of AZ or Pfizer Associated with Substantial Risk Reductions of COVID-19 Related Hospitalizations in Patients Over 80, Third Dose of mRNA Vaccine Improves Response in SOT Patients, Study on the Safety and Efficacy of Heterologous Vaccine Regimen

June 29, 2021

COVID-19 – ACIP Findings on Myocarditis/Pericarditis Associated with mRNA Vaccines, Delta Variant in Israel, Increase in Healthcare Organizations Mandating Vaccinations, Replacement of Alpha Variant with Delta Variant in US, CDC Report on Vaccine Reluctance in 18-39-Year-Olds, Transmission from Undiagnosed Patients to Roommates, Effect of Vaccination on Household Transmission

June 25, 2021

COVID-19 – OSHA Guidance for Workplace Safety, RCT Assessing Effectiveness of Comprehensive Preventive Intervention for a Mass-Gathering Indoor Event, Review on Mucor in India During the COVID-19 Surge, Tofacitinib in the Treatment of Severe COVID-19, Treatment of MIS-C

June 22, 2021

COVID-19 – ACIP Myocarditis Meeting Postponed, CDC Labels Delta VOC, US Death Toll Exceeds 600,000, CDC Posts Interim Guidance on Evaluating Post-COVID-19 Syndrome, Persistent Symptoms Following COVID-19 Infection, Effects of REGEN-COV with Standard Care, Vaccine Response in Patients with AIIRD, Influence of Two Vaccines on Delta Variant Infection and Admissions

June 18, 2021

COVID-19 – Editorials on Religious Exemptions and Mandatory Vaccinations, Report on a Rare Complication with AstraZeneca Vaccine, EMA Safety Committee Restriction on AstraZeneca Vaccine, Moderna Applied for EUA for 12-18 Year-Olds, Encouraging Late-Stage Data Reported from Novavax Vaccine, CDC Encouraging Hospitals and Emergency Care Facilities to Administer Vaccines to Unvaccinated Patients, Increase in New US Cases, Significant Reduction in Cases and Severity in High Vaccination Areas, Therapeutic Versus Prophylactic Anticoagulants in COVID-19 Patients, RNA Levels in Infected Symptomatic and Asymptomatic Adults and Children

June 14, 2021

COVID-19 – Concerning Global Spread of Delta Variant, ACIP to Review Possible Link of mRNA Vaccines and Myocarditis in Young Males, Growing Number of Healthcare Systems Moving to Mandatory HCW COVID-19 Vaccinations, Incidence of RSV in Southern Half of US, Children Unlikely to be Driving Transmission During the Pandemic, Natural Infection Provides Protection Against Re-Infection for at Least 5 Months, Infections in Vaccinated Individuals Have Significantly Reduced Viral Loads, Risk of CVST and ITP After Vaccination

June 11, 2021

COVID-19 – Latest Case Count in the US, Canada to Allow Vaccine Mixing After First AstraZeneca Dose, SC Injection Approval for Regeneron Monoclonal, CDC Report on Adolescent Hospitalizations for COVID-19 Versus Flu, Report on Myocarditis After Pfizer Vaccine in Adolescents, Incidence of Co-Bacterial Infections in COVID-19 Patients

June 8, 2021

COVID-19 – IDSA Guidelines on Rapid Antigen Testing, WHO EUA of a Second Chinese Vaccine, WHO to Start Labeling SARS-CoV-2 Variants Based on the Greek Alphabet, Comparing Methylprednisolone Versus Dexamethasone for Patients Hospitalized with COVID-19, Risk of Reinfection After Natural Infection in Two Different Countries, Simulated COVID-19 Transmission and Progression Using Different Assumptions of Vaccine Efficacy, Coverage, and Use of NPI

June 4, 2021

COVID-19 – HHS No Longer Recommends Lilly Monoclonal, NIH Revision on the Use of Baricitinib, Review on Summer Camp Recommendations, Immunosuppression by Certain Drugs and Response to COVID-19 Vaccines

June 1, 2021

COVID-19 – Ongoing Investigation of SARS-CoV-2 Origin, FDA Against Antibody Testing to Determine Immunity, EUA Issued by FDA for Sotrovimab, Persistent Cellular Immunity Against SARS-CoV-2 for at Least a Year, Efficacy and Safety of Pfizer Vaccine in Adolescents Ages 12-15

May 28, 2021

COVID-19 – VaST Report on Myocarditis Following mRNA Vaccines, Preliminary Data on Efficacy of Moderna Vaccine in Children 12-17, Use of Tocilizumab in Moderate COVID-19 Patients with High CRPs, Model on Aerosolized SARS-CoV-2 in an Electrocautery Plume, Comparison of 2 Rapid Molecular Assays for Detection of SARS-CoV-2, CDC Update on SARS-CoV-2 Vaccine Breakthroughs

May 26, 2021

COVID-19 – Latest US COVID-19 Numbers, Risk of Developing Symptomatic COVID-19 from B.1.617.2 Reduced by 88% after Two Pfizer Doses, Mucormycosis Infecting Thousands of COVID-19 Survivors in India, Latest Kaiser Study on Vaccine Acceptance, Review of MIS-A from Vanderbilt, Real-World Effectiveness of mRNA Vaccines in a Vulnerable Nursing Home Population, Gray Matter Loss in Older Individuals Infected with SARS-CoV-2

May 24, 2021

COVID-19 – More Healthcare Organizations Opting for Mandatory Vaccinations, Placenta Pathology in Women Vaccinated During Pregnancy, Systemic Review on Co-Infection and Superinfection in Patients with COVID-19, Late Uptick for RSV Infections, Meta-Analysis on Use of Anakinra in Treatment of Patients Infected with COVID-19

May 21, 2021

COVID-19 – Hospital and Vaccine Trends, RECOVERY Trial Results on Convalescent Plasma, Variant Neutralization Escape in Vaccine-Induced Humoral Immunity, Convalescent Plasma IgG Response to SARS-CoV-2

May 19, 2021

COVID-19 – Immunogenicity of mRNA Vaccines in Pregnancy and Lactating Women, Delayed Local Hypersensitivity Reactions to Moderna Vaccine, Vaccine Neutralizing Response Against B.1.167.1, Outline on How to Study Vaccine Efficacy in Cancer Patients

May 17, 2021

COVID-19 – FDA EUA for Pfizer Vaccine for Children 12-15, WHO Adds B.1.617 as Variant of Concern, Obesity and Adverse Outcomes After Infection with SARS-CoV-2, RECOVERY Trial on Tocilizumab, Danish and Norwegian Experience and Possibility of Hemostatic Events with the AstraZeneca Vaccine

May 12, 2021

COVID-19 – Editorial on Herd Immunity, WHO Approves EUA for China's Sinopharm Vaccine, Updated CDC Guidance on Transmission, Hand Hygiene Compliance During the Pandemic, Follow Up on Efficacy of Pfizer Vaccine in Israeli HCW, Role of Memory T-Cells

May 10, 2021

COVID-19 – Pfizer has Applied for Full FDA Approval, WHO Established Threat Levels for Variants, Canada has Approved Pfizer Vaccine for Children 12-15, Efficacy of Novavax Vaccine Against B.1.3551, Vaccination Highly Effective at Preventing Infection with B.1.1.7 and B.1.351, Vaccine More Than 95% Effective at Protecting Against Hospitalization and Death Among Fully Vaccinated People 16 and Over, Reinfection in Patients Who Have Recovered from Natural Infection

May 7, 2021

COVID-19 – FDA Expected to Approve Vaccination in Children 12-15, Review on Lung Transplants for Severe SARS-CoV-2, Pandemic has Disproportionately Affected Minority Groups, Impact of the P.1 Variant in Brazil

May 5, 2021

COVID-19 – Editorial on Opening Schools, Infection Rate Among Students and Staff in NYC Public Schools, Caregiver Perceptions of Children's Psychological Wellbeing, Maternal SARS-CoV-2 and Neonatal Outcomes, NBA Closed Campus Model Confirms CDC Guidance on Symptom-Based Isolation Discontinuation, Value of 1 Vaccine Dose on Household Transmission

May 3, 2021

COVID-19 – Updated CDC Guidance on Healthcare Infection Prevention and Control Recommendations in Response to COVID-19 Vaccination, Update on Vaccine Slowdown, Human to Cat Transmission in the UK, Efficacy of mRNA Vaccines in Persons Over 65, Vaccine Side Effects and Efficacy in Two Vaccines in the UK, Decreased Viral Load After One Dose of Pfizer Vaccine

April 30, 2021

COVID-19 – Safety of Vaccination in Pregnancy, Mask Mandate Relaxation, Comparison of Saliva, Throat, and NP Testing, Infection of the Oral Cavity and Saliva, Cleveland Genomic Study from First SARS-CoV-2 Wave

April 28, 2021

COVID-19 – US Resuming J&J Vaccinations, Update on Influenza Versus COVID-19, NIH Updates, VA Dataset on Long Term Sequelae from Veteran who Survived SARS-CoV-2, Invasive Aspergillosis in Influenza Versus COVID-19, Simulation on Impact of Testing of Children and Transmission

April 26, 2021

COVID-19 – New Pediatric Cases Up, Interim Report on Novavax Vaccine, Safety and Efficacy of One Dose J&J Vaccine, mRNA Vaccines Safe During Pregnancy, Convalescent Plasma Treatment in Hospitalized Patients

April 23, 2021

COVID-19 – FDA Revoked Bamlanivimab EUA, EMA Concluded Benefits Outweigh Risks of J&J Vaccine and Add Blood Clot Warning, Updated CDC Travel Advisory, Incidence of Acute Allergic Reactions to mRNA Vaccines, SARS-CoV-2 Transmission in Georgia School District, Reinfection Not More Likely with B.1.1.7 Variant

April 21, 2021

COVID-19 – Current Status of Vaccines, Vaccine Response in Chronic HD Patients, Even in Older NH Population a Single Dose May Be Sufficient in Patients with Prior Infection, Vaccine-Induced ITT

April 19, 2021

COVID-19 – CDC Report on Breakthrough COVID-19 in Fully Vaccinated People, Update on J&J Vaccine Review, Possible Breakthrough Rates of Variants of Concern in mRNA Vaccinated People, Response to Single Dose Pfizer or AstraZeneca Vaccine, Anticoagulants in Hospitalized COVID-19 Patients, Diagnosed CVT in COVID Patients vs Recipients of First Dose mRNA Vaccine

April 16, 2021

COVID-19 – J&J Vaccine Pause, Mechanism of Rare Thrombotic Event Associated with AstraZeneca Vaccine, Previous History of Infection Associated with 84% Lower Risk of Infection, Increased Transmissibility of B.1.1.7, AstraZeneca Vaccine Still Maintains Strong Protection Against B.1.1.7

April 14, 2021

COVID-19 – Initial Results of SQ Regeneron in Exposed Household Contacts, Revised NIH Guidance on Monoclonals, Pfizer Seeking EUA for Children 12-15, Impact of Prophylactic Anticoagulants at Discharge on Major Thromboembolic Events, Long Term Symptoms in HCP with Mild COVID-19, Vaccines and Plasma Neutralizing Activity Against Wild Type and Variants

April 12, 2021

COVID-19 – B.1.1.7 Most Common Variant in the US, Rand Report Shows Decline in Trust in the CDC, AstraZeneca Vaccine Update, Impact of Psychiatric Disorders and Outcomes from COVID-19, Observational Trial on Tocilizumab, Performance of Saliva, Oropharyngeal Swabs, and Nasal Swabs for SARS-CoV-2 Molecular Detection

April 9, 2021

COVID-19 – CDC Update on Disinfection, AstraZeneca Children's Study Put on Hold, Clinical Phenotypes and Associated Comorbidities and Complications, Seasonal Coronavirus Reinfections, Community Spread from a Rural Bar Opening in Illinois, Large Cross-Sectional Analysis on MIS-C

April 7, 2021

COVID-19 – New CDC Travel Guidance, AAP and CHA Joint Report on New Pediatric Infections, Impact of COVID-19 on Mortality in 2020

April 5, 2021

COVID-19 – Preliminary Pfizer Report on Vaccine Efficacy in Children 12-16, WHO Report on COVID Origin, Lilly's BLAZE-1 Phase 3 Study on Combined Bamlanivimab/Etesevimab Therapy, Sensitivity of Variants to Neutralizing Antibodies, Escape of SARS-CoV-2 501Y.V2 from Neutralization by Convalescent Plasma, CDC Report on Interim Estimates of mRNA Vaccine Effectiveness Among HCP and Essential and Frontline Workers, Review on "Long-Haulers"

March 31, 2021

COVID-19 – Vaccine Response in Pregnant and Lactating Women, Biomarkers and Risk Stratification, Remdesivir Update, Combination Steroid and Tocilizumab Therapy in the Elderly

March 29, 2021

COVID-19 – Challenges of Vaccinating Cancer Patients and Transplant Patients, COVID-19 Associated Pulmonary Aspergillosis, Symptoms/Symptom Clusters and Predictors for Becoming a "Long-Hauler", Widespread and Effective Vaccination Among Healthcare Workers

March 26, 2021

COVID-19 – Update on AstraZeneca Vaccine Data, IDSA Update on Monoclonals and Changes in Distribution of Bamlanivimab Based on Variants, Challenges of Reducing Transmission in Persons Without Symptoms, Use of ASA and Outcomes, Review on Pregnancy, Postpartum Care, and COVID Vaccination

March 24, 2021

COVID-19 – CDC Operational Strategies for K-12, B.1.1.7 Variant in the US, Vaccine Manufacturing and Projection, Snapshot of Vaccinations in the US, KFF/Washington Post Survey on Vaccine Acceptance in Front line Healthcare Workers, Changing Physical Distancing in Classrooms from 6 ft. to 3 ft.

March 22, 2021

COVID-19 – Updated European Review of AstraZeneca Vaccine, Impact of Vaccinations and COVID Infections in SNFs, Risk of Reinfection in Denmark, Does Vaccination Impact Risk of Asymptomatic Infection?

March 19, 2021

COVID-19 – Editorial on Social Distancing Protocols and Opening Schools, Pfizer Data on Preventing Asymptomatic Disease in Israel, Vaccine Trials in Children 6 Mos.-11 Yrs., Updated IDSA/AMP Statement on Ct Thresholds for Clinical Decision Making, B.1.1.7 Potentially Associated with Higher Mortality, 3 Ft. vs. 6 Ft. Social Distancing, Effectiveness of AstraZeneca Vaccine Against B.1.351, Marked Increase in CLABSIs During the Pandemic

March 17, 2021

COVID-19 – Aerosol Transmission and PPE, Super-Spreaders Tend to be Obese or Older/in Elder Care or Hospitalized, Revised CDC Guidance on PPE in February, Aerosol Generating Procedures

March 15, 2021

COVID-19 – COVID and Overuse of Antibiotics, Antibody Resistance to Some Mutants, Is Infection with the B.1.1.7 Variant More Lethal, Antibody Response to mRNA Vaccines in Previously Infected Persons

March 12, 2021

COVID-19 – CDC Guidance for Fully Vaccinated People, Vaccination Potentially Reduces Transmission, Pfizer Vaccine Neutralizes B.1.351 and P.1 Variants, Local Reactions to mRNA Vaccines, Vizient Clinical Database Data Analysis Regarding Outcomes and Mortality in Hospitalized COVID Patients, Morbid Obesity May Increase Severity and Mortality in Infected Patients

March 10, 2021

COVID-19 – Preliminary Findings from the RECOVERY Colchicine Trial, Updated NIH Guidelines on Tocilizumab, New Antiviral Molnupiravir, Association of Infections with State-Mandated Masks and Allowance of On-Premises Dining, Effect of Early Treatment with Fluvoxamine in Preventing COVID Progression, Effect of Ivermectin in Patients with Mild COVID, Identification of SARS-CoV-2-Specific Immune Alterations

March 8, 2021

COVID-19 – Houston Genomic Surveillance Analysis, Impact of HAIs during COVID, PCT May Be Helpful Evaluating COVID Patients for Administration of Antibiotics

March 5, 2021

COVID-19 – Editorial on Texas's Ease of Restrictions, Thromboprophylaxis, Humoral and T-Cell Response to Single Vaccine Dose in Persons with Prior COVID Infection, Effect of Antecedent Statin Use on Mortality

March 3, 2021

COVID-19 – FDA and CDC Approve EUA for J&J Vaccine, Positive Outcomes for Monoclonal Front-Combination Treatment on High Risk Outpatients with Mild-to-Moderate Disease, Transmission in Fitness Facilities, Review and Meta-Analysis on RCTs for Convalescent Plasma, Different Outcomes in Interleukin-6 Receptor Antagonist Studies

March 1, 2021

COVID-19 – FDA Review on J&J Vaccine, New Variants in California and New York, Report on Dramatic Decline in Nursing Home Deaths, Estimated Vaccine Effectiveness After Israel Vaccine Rollout, Maternal Infection Relation to Preterm Delivery, Distinguishing Between MIS-C and Severe Acute COVID-19 in Children.

February 26, 2021

COVID-19 – Role of Vaccinations in Public Health, Influence of Booster Dose Timing on Immunogenicity and Efficacy in AstraZeneca Vaccine, Over-Application of Antibiotics, Sequalae of COVID After 6 Months

February 24, 2021

COVID-19 – Impact of Zinc, Vitamin C and D, Early Reductions in Infection and Symptomatic Rates Following First Pfizer Vaccine Dose, Review and Meta-Analysis on Convalescent Plasma Therapy

February 22, 2021

COVID-19 – Global Emergence of Spike Protein Variants, Neutralizing Activity of Moderna and Pfizer Vaccines, Discovery of Large Cell Nuclei Morphologically Consistent with Megakaryocytes in Small Sample of Brain Capillaries, Association of Viral Load and Outcomes

February 19, 2021

COVID-19 – New CDC Evidence and Recommendations for Immunocompromised Adult Isolation Procedures and Precautions, Updated UK Findings on B.1.1.7 Variant, Evidence Why B.1.1.7 May Be Transmitting More Rapidly, Who May Be Superspreaders, 13 COVID Research Priorities from Surviving Sepsis Committee

February 17, 2021

COVID-19 – FDA Granted EUA for Combination Monoclonal Bamlanivimab and Etesevimab, CDC Guidance on Quarantine for Vaccinated Individuals, CDC Report on Double Masking, Updated ACP Guidance on Remdesivir, RECOVERY Results on Tocilizumab

February 12, 2021

COVID-19 – 2021 Editorial, Update on Current Rates in US, Merck Release on Ivermectin, Study on IL-1 and IL-6 Inhibitors, Nasal and Oral Antiseptics Against SARS-CoV-2, Duration of Culturable Virus in Hospitalized Patients with Mild to Moderate Disease

February 11, 2021

COVID-19 – FDA Revised Guidance on CP, AstraZeneca Vaccine Trial in South Africa, Retrospective on Adding Methylprednisolone to IVIGs in Multisystem Inflammatory Syndrome in Children, Single Dose AstraZeneca Vaccine

February 8, 2021

COVID-19 – J&J Vaccine Submitted to FDA for EUA, Revised NIH Guidelines on Tocilizumab, OSHA Guidance on Preventing Infection Spread in Workplaces, Contribution to Spread by Age Groups, Co-Bacterial Infections in COVID Patients Admitted to Hospitals Very Low, Transmission Risk Primarily Driven by Viral Load of Index Cases/Risk Stratification of Newly Diagnosed SARS-CoV-2 Infections Based on Initial Viral Load

February 5, 2021

COVID-19 – Astra Zeneca Vaccine Update, New Mutant E484K, Review on Long Term Effects of COVID, Interim Analysis of Phase 3 Trial of Sputnik 5, Vaccine Response Between Seropositive and Seronegative Individuals

February 3, 2021

COVID-19 – CDC Travel Masking Requirements, J&J Vaccine Announcement, Antibodies in Infants Born to Mothers with SARS-CoV-2 Antibodies, SSC Update on COVID-19

February 1, 2021

COVID-19 – Novavax Vaccine, B1.351 Variant, Pre Publication Examining Neutralization of Two Variants by Vaccine-Elicited Sera, Colchicine as Outpatient Treatment for High-Risk Patients, Effects of Anakinra in Patients with Mild-to-Moderate COVID Pneumonia, Experience of K-12 This Past Fall

January 29, 2021

COVID-19 – Transition from Pandemic to Endemic, Clinical Characteristics and Outcomes of Women Giving Birth With and Without COVID-19, In-Flight Transmission Despite Predeparture Testing

January 18, 2021

COVID-19 – New CDC Requirements for International Travelers to the US, REMAP-Cap Trial Announcement on Convalescent Plasma, Mayo Clinic Findings on Convalescent Plasma, COVID Trends in Persons 0-24, Phase 1/2 Findings on Ad26.COV2.S Vaccine

January 15, 2021

COVID-19 – HHS Releasing Reserved Vaccine Doses, Ages 65+ Now Eligible for Vaccine, Long Term Impact on Recovered Patients, Gut Microbiota and Dysfunctional Immune Response, Review on Testing Sensitivity and Costs of Saliva vs. Nasopharyngeal Swab

January 13, 2021

COVID-19 – Molecular Tests vs. Variants, IDSA Updated Treatment Guidelines, IL-6 Receptor Antagonists, Pfizer Vaccine Looks Effective Against B.1.1.7, Transmission from Asymptomatic Individuals, Incidence and Secondary Transmission in Schools

January 11, 2021

COVID-19 – CDC Updated mRNA Vaccine Contraindications and Precautions, FDA Response to Alternative Vaccine Schedules, Publications in Favor of Alternative Vaccine Schedules, Rapid Antigen Test vs. PCR, Small Canakinumab Study, Impact of Tiered Restrictions and Lockdowns

January 6, 2020

COVID-19 – Variant B.1.1.7, Review on Vaccination Updates, AIM Masking Updates, the Science Behind Moderna Vaccine, Review on Prevalence and Characteristics of Taste Disorders in COVID

January 4, 2020

COVID-19 – Turning the Corner on COVID Editorial, Novavax and Astra Zeneca Vaccine Reviews, Confirmation of Variant B.1.1.7 in Colorado, Antibody Status and Incidence of Infection in HCWs, IDSA Guidelines on Diagnosis

December 30, 2020

COVID-19 – Options for Moving Ahead with Investigational Vaccines, Specific Memory B Cells Indicate Retained Immunity in Patients, ACAAI Updated Guidance on Risk of Allergic Reaction to mRNA Vaccines, Monoclonals with Remdesivir Did Not Demonstrate Efficacy in Hospitalized Patients, Variation in US Hospital Mortality Rates

December 28, 2020

COVID-19 – New Variant, Lack of Genomic Surveillance in the US, Two Approaches to Stretch the Number of Available Vaccine Doses, ACEI and ARBs Not Associated with More Severe Disease, Glycemic Control and Clinical Outcomes, COVID Infections and Cancer

December 23, 2020

COVID-19 – CDC's New Priority Groups, Close Contact/Gatherings Associated with Infections in Children/Adolescents as Opposed to School Attendance, Patients Most Likely to Benefit from Tocilizumab, Interim Report on Regeneron Monoclonal, New Mutation Reported from the UK

December 22, 2020

COVID-19 – Incidence of Influenza and Other Respiratory Viruses, Moderna Vaccine Approval, Influenza Contrasted with COVID-19 in Hospitalized Patients, Metapopulation SEIR Model to Guide Reopening and Shutdowns, Evidence Base for Vaccine Prioritization and Allocation, Lower COVID Risk Among Younger Adults Not Borne Out by Evidence

December 18, 2020

COVID-19 – Vaccinations Have Begun, ACOG Guidelines on Vaccination, Updated NIH Treatment Guidelines on Baricitinib Plus Remdesivir, Initial Review of Moderna Vaccine, WHO Update on Masking, FDA Authorized First Over the Counter At-Home COVID Test, GBS and COVID-19, Evaluation of Cloth and Modified Procedure Masks, Prepublication Result on Azithromycin and COVID-19, Pandemic Impact on Immunization in Colorado

December 16, 2020

COVID-19 – Current Statistics and Projections, Vaccinations Begin This Week, CDC Advisory Committee Vaccine Report, Baricitinib Plus Remdesivir ACTT-2 Trial, Positive Blood Cultures During the Pandemic, Superspreader Genomic Study

December 14, 2020

COVID-19 – Pfizer Vaccine Approval, Implementation Over Efficacy, Mortality Due to Cancer Treatment Delay, Diagnosis-Wide Analysis of COVID-19 Complications

December 11, 2020

COVID-19 – FDA Analysis of Pfizer Vaccine Data, Metformin Use and its Effect on Mortality, Admission Hyperglycemia Strong Predictor of Mortality in Hospitalized Patients, AstraZeneca Vaccine Interim Results, Safety Confirmation for Rooming-In/Breastfeeding for COVID-Positive Mothers, Role of Children in Household Clusters

December 9, 2020

COVID-19 – Editorial: Summary and Discussion of New CDC Public Health Guidance

December 7, 2020

COVID-19 – ACIP Recommendations for Phase 1a Vaccination, UK EUA for Pfizer Vaccine, Updated CDC Quarantine Recommendations, Shanghai School Reopening Models, Transmission Heterogeneity, Mental Health in Older Adults Amid Pandemic, Current Treatment Modalities for Severe COVID-19

December 2, 2020

COVID-19 – CDC May Update Quarantine Recommendations, Vaccine Updates, Estimated US Seroprevalence, Estimated US Incidence of Illness and Hospitalization, Convalescent Plasma for Severe Pneumonia Randomized Trial, Prognosis in Patients Based on Glycemic Control

November 30, 2020

COVID-19 – Vaccine News, Baricitinib/Remdesivir Combo and Regeneron Receive FDA EUAs, Efficacy vs. Effectiveness, Composite Nasal Spray, Delirium in Older Patients

November 23, 2020

COVID-19 – Infections in HCWs at the Mayo Clinic, FDA Approved At-Home Test, NIH Guidelines for Bamlanivimab, Updated WHO Recommendation for Remdesivir, Danish Mask Study, Duke University COVID Mitigation Successful, Prepublication on Immunological Memory

November 20, 2020

COVID-19 – Vaccine News, ESICM Statement on Remdesivir, Expanding Understanding of Immune Response Focused on IFN, Fluvoxamine as a Potential Mechanism for Immune Modulation

November 18, 2020

COVID-19 – The State of the Pandemic November 16, 2020

November 16, 2020

COVID-19 – Persistent Fatigue Following SARS-CoV-2 Infection, Age and Personal and Social Reactions to COVID-19, Transmission among Marine Recruits During Quarantine, Preexisting and De Novo Humoral Immunity

November 13, 2020

COVID-19 – Same-Hospital Readmission Characteristics, Use of Ivermectin Associated with Lower Mortality, Hydroxychloroquine Randomized Clinical Trial

November 11, 2020

COVID-19 – Routine Testing Frequency in Healthcare Environments, Distinct Antibody Responses in Children and Adults, Systematic Review of Multisystem Inflammatory Syndrome in Children, Risk-Adjusted Mortality Rates

November 9, 2020

COVID-19 – Rapid Test False-Positive Results, Potential Cardiac Involvement in Competitive Athletes, AAP/CHA Updates in Pediatric Cases, Prolonged Infectious Shedding in Asymptomatic Immunocompromised Cancer Patient

November 6, 2020

COVID-19 – SARS-CoV-2 Infection and Pregnancy, Infections Among HCPs in Minnesota, Infections in Household Contacts, Effect of Age on Transmission, Risk Factors for Transmission Among Patient Close Contacts

November 4, 2020

COVID-19 – Testing in Schools, Three Quarters of Infected Asymptomatic in English Household Survey, Infection Fatality Ratio, Clinically Identifiable Autoreactivity

November 2, 2020

COVID-19 – Outlook Editorial, Trends in NPI Outcomes, COVID-Positive Breastfeeding Best Practices, Hospitalizations Among HCP, Efficacy/Outcomes of Tocilizumab

October 28, 2020

COVID-19 – Updated CDC Definition of Close Contact, Convalescent Plasma in Management of Moderate COVID-19, Modeling Scenarios for the US, Lowering Transmission and Spread

October 26, 2020

COVID-19- Reinfection, Revised NIH Guidelines, Update on Plasma, COVID-19 and HIV, and a Look at Vertical/Perinatal Transmission

October 14, 2020

COVID-19 – Remdesivir Treatment, Baricitinib plus Remdesivir, Final Report on HCQ from the RECOVERY Trials, and Lopinavir–Ritonavir Combination Therapy

October 12, 2020

COVID-19 - Cytokine Storm in the Pathogenesis of Severe SARS-CoV-2 and the Great Barrington Declaration

October 9, 2020

COVID-19 - Multisystem Inflammatory Syndrome in Adults, Transmission in India, CDC on Airborne Transmission (Revised), and Neurological Manifestations

October 7, 2020

COVID-19 - Endothelial Injury and the Pathogenesis of SARS-CoV-2 Infection, Loss of Smell vs Loss of Taste, Role of Vitamin D in SARS-CoV-2 Infection

October 5, 2020

COVID-19 – College Infections, Tocilizumab Treatment, Plasma Treatment, Hydroxychloroquine for Prophylaxis (No Apparent Benefit), Adjusted Early Pandemic Ro

October 2, 2020

COVID-19 – Susceptibility in Children, Innate Immune Response in Children, Protective Role of Type 1 Interferons, and GI Complications

September 28, 2020

COVID-19 – Genomic Analysis of SARS-CoV-2 Strains in 2 Infection Waves in Houston, Predicting Disease Severity, Influence of SARS-CoV-2 on Influenza in Northern and Southern Hemispheres

September 25, 2020

COVID-19 – Eyeglasses Could Potentially Provide Some Protection, CDC Update on Testing, Activity of PI Intranasally Against SARS-CoV-2, Empacta Trial

September 21, 2020

COVID-19 – Deaths in Persons Under 21, CDC Indicators for Opening Schools, Maternal and Birth Outcomes in Hospitalized Pregnant Women, and Current Science on Transmission of SARS-CoV-2

September 18, 2020

COVID-19 – Consequences of Delaying Care, Guide for COVID-19 Survivors with Silent Myocarditis, Child-to-Child Transmission in Schools After Germany Reopening in May 2020, Transmission Dynamics of COVID-19 Outbreaks in Utah Child Care Facilities, and Overnight Camps

September 14, 2020

COVID-19 – Steroid Clinical Trial, Increase in SARS-CoV-2 in Younger Adults, Importance of Large Deidentified Datasets for Answering Important Questions, Exposures in Restaurants, and Nosocomial Infections

September 11, 2020

COVID-19 – Antithrombotic Therapy, Masking, Contrasting COVID-19 with Seasonal Flu in Children this Year, and Cytokine Levels in Critically Ill Patients

September 9, 2020

COVID-19 – Impact on Mental Health, Russian Vaccine, Other Vaccines, and Transmission from Healthcare Workers

September 8, 2020

COVID-19 – Steroids, RECOVERY Dexamethasone Trial, and Infection Fatality Ratio Among Noninstitutional Persons

September 4, 2020

COVID-19 – Airborne Transmission and Protection from Neutralizing Antibodies

September 2, 2020

COVID-19 – Reducing Transmission in Children, Reduced Vitamin K in Severe Cases, Saliva vs. NP PCR Detection of Virus

August 31, 2020

COVID-19 - Safe Reopening of College, Frequency and Turnaround Time for Surveillance, Isolation Time, Predictive Cytokine Signature, Disease Outcomes Based on Sex Differences, and More

August 28, 2020

COVID-19 – Reinfection, Asymptomatic Cases in Children, Post-discharge Quality of Life, Asymptomatic Spread, CDC on Testing Asymptomatic Cases

August 26, 2020

COVID-19 -Convalescent Plasma, Remdesivir Optimal Patient Population and With or Without Dexamethasone, IDSA Guidance on Serologies, and Antigen Tests

August 24, 2020

COVID-19 – Antimicrobial Stewardship for COVID-19 Patients, Endothelial Injury in Severe SARS-CoV-2 Infection, More on Infection in Children

August 21, 2020

COVID-19 – Houston Experience Review, POC Treatment of Severe SARS-CoV-2 Pneumonia with Adipose-Derived Mesenchymal Stromal Cells, Convalescent Plasma, Using Datasets to Analyze Pandemic, T1 and T2 Diabetes and Mortality, and High Transmission When Not Opening Safely

August 17, 2020

COVID-19 Pediatric Focus; T Cell Recognition and Cross-Reactive Immunity from Other Coronavirus Exposure, Child Hospitalizations; Steroid Use in Ventilated Patients

August 12, 2020

COVID-19 - Viral Shedding Among Asymptomatic and Symptomatic Patients, Imaging in Patients, and Estimating Incubation Periods

August 10, 2020

COVID-19 – Risk of Household Contacts with Older Children, Infant Infection, Early ID of Cytokine Storm Various Treatment Strategies with Anakinra or Tocilizumab

August 7, 2020

COVID-19, Convalescent Plasma, Vitamin D, Quarantine Time Based on Detection of Live Virus vs. Viral RNA, and Cardiovascular Injury

August 5, 2020

SARS-CoV-2 Airborne Transmission Controversy

August 3, 2020

COVID-19 – Hopkins Document, Timing of SARS-CoV-2 Detection, Reopening Schools, Vaccine Results in Nonhuman Primates

July 31, 2020

COVID-19 Neonatal and Obstetrical Outcomes, Remdesivir Trial, Rapid Antibody Decay, and Plasma Exchange Treatment

July 29, 2020

Remdesivir Supply, Methylprednisolone/Toclizumab Treatment, CDC Guidelines for Reopening K-12, and Symptom Duration

July 27, 2020

COVID-19 Seroprevalence Surveys, Less Common Symptoms, Thrombosis, and Astrazeneca Vaccine

July 22, 2020

COVID-19 CDC Guidance, Transmission by Children, PICU NY Experience, and Transplacental Infection

July 20, 2020

COVID-19 Dexamethasone Recover Trial

July 18, 2020

COVID-19 Community Transmission and Opening Schools, Hydroxychloroquine, ICU Cases and Mortality Rates

July 17, 2020

COVID-19 Airborne Transmission, Masks are Protective, Tocilizumab, and Moderna mRNA Vaccine

July 15, 2020