Please join us for the Center for Neuroregeneration Lecture Series: Cell and Molecular Events Leading to Age-Related Neurodegenerative Disease with Fred H. Gage, PhD, The Salk Institute.

Age is the greatest risk for age-related neurodegenerative disease. In Cell and Molecular Events Leading to Age-Related Neurodegenerative Disease, Fred H. (Rusty) Gage will discuss his team’s work using direct conversion of primarily sporadic Alzheimer’s disease patient fibroblasts into induced neurons (iNs) to generate an age-equivalent neuronal model. Patient-derived iNs exhibit strong Alzheimer’s disease-specific transcriptome neuronal signatures characterized by down-regulation of mature functional and morphological properties and up-regulation of immature neuronal and neural stem cell-associated pathways.

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When: October 17, 2023, from 9-10:30 am (CDT)
Where:  Houston Methodist Research Institute, RI Auditorium
             6670 Bertner Avenue, Houston, TX

Contact: Dee Lofton, dloftin@houstonmethodist.org